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DNA-Protein Interaction of gamma-Globin Gene Promoter by Differentiation Inducers

Kim DI, Park JI, Kim IH

  • KMID: 2143367
  • Korean J Hematol.
  • 1999 Aug;34(3):436-444.
BACKGROUND: The K562 erythroleukemia cell line was used to study the molecular mechanisms regulating lineage commitment of hematopoietic cells. There are numerous similarities between the erythroid or megakaryocytic lineages. In...
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Role of Gamma Globin Promoter Region -269~-240 in Hydroxyurea Treated Erythroid Progenitor Cells

Park JI, Kim TG, Kim DI, Kim IH, Jeong JS, Han JY

  • KMID: 1863286
  • Korean J Clin Pathol.
  • 1998 Mar;18(1):29-34.
BACKGROUND: Recently, a great deal of interest has been focused on the use of hydroxyurea and hemin that may augment Hb F levels in patients with hemoglobinopathies and thalassemia, although...
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