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Editorial for ‘Lower Urinary Tract Symptoms: Clinical and Translational Science’

Birder LA

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Corrigendum: Improved Urothelial Cell Proliferation, Cytoskeleton and Barrier Function Protein Expression in the Patients With Interstitial Cystitis/Bladder Pain Syndrome After Intravesical Platelet-Rich Plasma Injection

Jhang JF, Jiang YH, Hsu YH, Ho HC, Birder LA, Lin TY, Kuo HC

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Oxidative Stress Biomarkers in Age-Related Lower Urinary Tract Disorders: A Systematic Review

Khosla L, Gong S, Weiss JP, Birder LA

Purpose: To conduct a systematic review of preclinical and clinical peer-reviewed evidence linking alterations in oxidative stress biomarkers or outcome measures that were also prevalent in specific age-related lower urinary...
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Quantification of Aging-Related Decreases in Sensory Innervation of the Bladder Trigone in Rats

Rijk MMd, Peter S, Wolf-Johnston A, Heesakkers J, Koeveringe GAv, Birder LA

Purpose: The prevalence of lower urinary tract symptoms (LUTS), characterized by problems regarding storage and/or voiding of urine, is known to significantly increase with age. Effective communication between the lower...
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Aging-Associated Changes in Oxidative Stress Negatively Impacts the Urinary Bladder Urothelium

de Rijk MM, Wolf-Johnston A, Kullmann AF, Taiclet S, Kanai AJ, Shiva S, Birder LA

Purpose: Lower urinary tract symptoms are known to significantly increase with age, negatively impacting quality of life and self-reliance. The urothelium fulfills crucial tasks, serving as a barrier protecting the...
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Stress-Induced Changes in Trophic Factor Expression in the Rodent Urinary Bladder: Possible Links With Angiogenesis

Rijk MMd, Wolf-Johnston A, Kullmann AF, Maringer K, Sims-Lucas S, Koeveringe GAv, Rodríguez LV, Birder LA

Purpose: Substantive evidence supports a role of chronic stress in the development, maintenance, and even enhancement of functional bladder disorders such as interstitial cystitis/bladder pain syndrome (IC/BPS). Increased urinary frequency...
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Improved Urothelial Cell Proliferation, Cytoskeleton and Barrier Function Protein Expression in the Patients With Interstitial Cystitis/Bladder Pain Syndrome After Intravesical Platelet-Rich Plasma Injection

Jhang JF, Jiang YH, Hsu YH, Ho HC, Birder LA, Lin TY, Kuo HC

Purpose: To investigate urothelial cell proliferation, cytoskeleton, inflammation, and barrier function protein expressions in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) after intravesical platelet-rich plasma (PRP) injections Methods: A total of...
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Impact of Aging on Urinary Natriuretic Peptides in Nocturia and Nocturnal Polyuria

Khosla L, Boroda JU, Salama J, Rahman SN, Gordon DJ, Moy MW, Akivis Y, Akivis A, Lazar JM, Weiss JP, Birder LA

Purpose: The pathophysiology of nocturia and nocturnal polyuria (NP), conditions that become more prevalent with aging, may in part be explained by changes in hormones involved in water homeostasis. The...
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Nocturnal Urine Production in Women With Global Polyuria

Monaghan TF, Kavoussi AM, Agudelo CW, Rahman SN, Michelson KP, Bliwise DL, Lazar JM, Birder LA, Alwis US, Walle JV, Wein AJ, Blaivas JG, Weiss JP, Everaert K

Purpose: Low nocturnal urine production (NUP) may be sufficient to rule out global polyuria (GP) in men. This study determines the sensitivity of indices for nocturnal polyuria (NP), defined as...
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