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Erratum to "Potential Role of Dietary Salmon Nasal Cartilage Proteoglycan on UVB-Induced Photoaged Skin" [Biomol. Ther. 32 (2024) 249-260]

Lee HR, Hong SM, Cho K, Kim SH, Ko E, Lee E, Kim HJ, Jeon SY, Do SG, Kim SY

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Erratum to "Bispecific Antibody-Bound T Cells as a Novel Anticancer Immunotherapy" [Biomol. Ther. 30 (2022) 418-426]

Cho J, Tae N, Ahn JH, Chang SY, Ko HJ, Kim DH

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Endoplasmic Reticulum Stress Activates Hepatic Macrophages through PERK-hnRNPA1 Signaling

Kwon A, Kim YS, Kim J, Koo JH

Endoplasmic reticulum (ER) stress plays a crucial role in liver diseases, affecting various types of hepatic cells. While studies have focused on the link between ER stress and hepatocytes as...
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Ginsenosides Decrease β-Amyloid Production via Potentiating Capacitative Calcium Entry

Cho YY, Park JH, Lee JH, Chung S

Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disorder characterized by extracellular amyloid plaques composed of amyloid β-peptide (Aβ). Studies have indicated that Ca 2+ dysregulation is involved in...
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Tumor Stroma as a Therapeutic Target for Pancreatic Ductal Adenocarcinoma

Lee DU, Han BS, Jung KH, Hong SS

Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis owing to its desmoplastic stroma. Therefore, therapeutic strategies targeting this tumor stroma should be developed. In this study, we describe the heterogeneity...
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Novel Potential Therapeutic Targets in Autosomal Dominant Polycystic Kidney Disease from the Perspective of Cell Polarity and Fibrosis

Ahn Y, Park JH

Autosomal dominant polycystic kidney disease (ADPKD), a congenital genetic disorder, is a notable contributor to the prevalence of chronic kidney disease worldwide. Despite the absence of a complete cure, ongoing...
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Lysophosphatidic Acid Receptor 1 Plays a Pathogenic Role in Permanent Brain Ischemic Stroke by Modulating Neuroinflammatory Responses

Tiwari S, Basnet N, Choi JW

Lysophosphatidic acid receptor 1 (LPA1) plays a critical role in brain injury following a transient brain ischemic stroke. However, its role in permanent brain ischemic stroke remains unknown. To address...
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Effect of Kaempferol on Modulation of Vascular Contractility Mainly through PKC and CPI-17 Inactivation

Yoon HJ, Moon HW, Min YS, Jin F, Bang JS, Sohn UD, Je HD

In this study, we investigated the efficacy of kaempferol (a flavonoid found in plants and plant-derived foods such as kale, beans, tea, spinach and broccoli) on vascular contractibility and aimed...
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Cordycepin Enhanced Therapeutic Potential of Gemcitabine against Cholangiocarcinoma via Downregulating Cancer Stem-Like Properties

Lee HK, Na YJ, Seong SM, Ahn D, Choi KC

Cordycepin, a valuable bioactive component isolated from Cordyceps militaris, has been reported to possess anti-cancer potential and the property to enhance the effects of chemotherapeutic agents in various types of...
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Quinic Acid Alleviates Behavior Impairment by Reducing Neuroinflammation and MAPK Activation in LPS-Treated Mice

Park Y, Paing YMM, Cho N, Kim C, Yoo J, Choi JW, Lee SH

Compared to other organs, the brain has limited antioxidant defenses. In particular, the hippocampus is the central region for learning and memory and is highly susceptible to oxidative stress. Glial...
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Exploring the Potential of Natural Products as FoxO1 Inhibitors : an In Silico Approach

Gupta A, Haldhar R, Agarwal V, Singh Rajput A, Chun KS, Han SB, Raj V, Lee S

FoxO1, a member of the Forkhead transcription factor family subgroup O (FoxO), is expressed in a range of cell types and is crucial for various pathophysiological processes, such as apoptosis...
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Unlocking the Therapeutic Potential of BCL-2 Associated Protein Family: Exploring BCL-2 Inhibitors in Cancer Therapy

Dakkak BE, Taneera J, El-Huneidi W, Abu-Gharbieh E, Hamoudi R, H. Semreen M, Soares NC, Abu-Rish EY, Alkawareek MY, Alkilany AM, Bustanji Y

Apoptosis, programmed cell death pathway, is a vital physiological mechanism that ensures cellular homeostasis and overall cellular well-being. In the context of cancer, where evasion of apoptosis is a hallmark,...
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Metabolomic Profiles in Patients with Cervical Cancer Undergoing Cisplatin and Radiation Therapy

Choi SY, Kim S, Jeon JY, Kim MG, Lee SY, Shin KH

This study was aimed to evaluate endogenous metabolic changes before and after cisplatin and radiation therapy in patients with cervical cancer via untargeted metabolomic analysis using plasma samples. A total...
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Morroniside Protects C2C12 Myoblasts from Oxidative Damage Caused by ROS-Mediated Mitochondrial Damage and Induction of Endoplasmic Reticulum Stress

Hwangbo H, Park C, Bang E, Kim HS, Bae SJ, Kim E, Jung Y, Leem SH, Seo YR, Hong SH, Kim GY, Hyun JW, Choi YH

Oxidative stress contributes to the onset of chronic diseases in various organs, including muscles. Morroniside, a type of iridoid glycoside contained in Cornus officinalis, is reported to have advantages as...
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Activation of Heme Oxygenase-1 by Mangiferin in Human Retinal Pigment Epithelial Cells Contributes to Blocking Oxidative Damage

Park C, Cha HJ, Hwangbo H, Bang E, Kim HS, Yun SJ, Moon SK, Kim WJ, Kim GY, Lee SO, Shim JH, Choi YH

Mangiferin is a kind of natural xanthone glycosides and is known to have various pharmacological activities. However, since the beneficial efficacy of this compound has not been reported in retinal...
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