- Erratum to "Carbon Monoxide Ameliorates 6-Hydroxydopamine-Induced Cell Death in C6 Glioma Cells" [Biomol. Ther. 26 (2018) 175-181]
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Moon H, Jang JH, Jang TC, Park GH
- KMID: 2531004
- Biomol Ther.
- 2022 Jul;30(4):389-389.
- doi: 10.4062/biomolther.2022.003
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- Strategies for Manipulating T Cells in Cancer Immunotherapy
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Lee HM
- KMID: 2530994
- Biomol Ther.
- 2022 Jul;30(4):299-308.
- doi: 10.4062/biomolther.2021.180
T cells are attractive targets for the development of immunotherapy to treat cancer due to their biological features, capacity of cytotoxicity, and antigen-specific binding of receptors. Novel strategies that can... -
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- Repeated Morphine Administration Increases TRPV1 mRNA Expression and Autoradiographic Binding at Supraspinal Sites in the Pain Pathway
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Nguyen TL, Nam YS, Lee SY, Jang CG
- KMID: 2530997
- Biomol Ther.
- 2022 Jul;30(4):328-333.
- doi: 10.4062/biomolther.2022.014
Repeated morphine administration induces tolerance to its analgesic effects. A previous study reported that repeated morphine treatment activates transient receptor potential vanilloid type 1 (TRPV1) expression in the sciatic nerve,... -
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- Metabolic Bone Diseases and New Drug Developments
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Natesan V, Kim SJ
- KMID: 2530995
- Biomol Ther.
- 2022 Jul;30(4):309-319.
- doi: 10.4062/biomolther.2022.007
Metabolic bone diseases are serious health issues worldwide, since several million individuals over the age of 50 are at risk of bone damage and should be worried about their bone... -
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- Peroxiredoxin 6 Overexpression Induces Anxiolytic and Depression-Like Behaviors by Regulating the Serotonergic Pathway in Mice
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Gu SM, Yu E, Kim YE, Yoon SS, Lee D, Hong JT, Yun J
- KMID: 2530998
- Biomol Ther.
- 2022 Jul;30(4):334-339.
- doi: 10.4062/biomolther.2021.169
Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase and calcium-independent phospholipase activity. Recently, we reported that PRDX6 plays an important role in dopaminergic neurodegeneration in Parkinson’s disease. However,... -
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- Snail Promotes Cancer Cell Proliferation via Its Interaction with the BIRC3
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Rho SB, Byun HJ, Kim BR, Lee CH
- KMID: 2531003
- Biomol Ther.
- 2022 Jul;30(4):380-388.
- doi: 10.4062/biomolther.2022.063
Snail is implicated in tumour growth and metastasis and is up-regulated in various human tumours. Although the role of Snails in epithelial-mesenchymal transition, which is particularly important in cancer metastasis,... -
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- Characterization of KRC-108 as a TrkA Kinase Inhibitor with Anti-Tumor Effects
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Lee HJ, Moon Y, Choi J, Heo JD, Kim S, Nallapaneni HK, Chin YW, Lee J, Han SY
- KMID: 2531001
- Biomol Ther.
- 2022 Jul;30(4):360-367.
- doi: 10.4062/biomolther.2021.195
Tropomyosin receptor kinase A (TrkA) protein is a receptor tyrosine kinase encoded by the NTRK1 gene. TrkA signaling mediates the proliferation, differentiation, and survival of neurons and other cells following... -
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- High Levels of Hyaluronic Acid Synthase-2 Mediate NRF2-Driven Chemoresistance in Breast Cancer Cells
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Choi BH, Ryoo I, Sim KH, Ahn Hj, Lee YJ, Kwak MK
- KMID: 2531002
- Biomol Ther.
- 2022 Jul;30(4):368-379.
- doi: 10.4062/biomolther.2022.074
Hyaluronic acid (HA), a ligand of CD44, accumulates in some types of tumors and is responsible for tumor progression. The nuclear factor erythroid 2-like 2 (NRF2) regulates cytoprotective genes and... -
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- Behavioral Deficits in Adolescent Mice after Sub-Chronic Administration of NMDA during Early Stage of Postnatal Development
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Adil KJ, Remonde CG, Gonzales EL, Boo KJ, Kwon KJ, Kim DH, Kim HJ, Cheong JH, Shin CY, Jeon SJ
- KMID: 2530996
- Biomol Ther.
- 2022 Jul;30(4):320-327.
- doi: 10.4062/biomolther.2021.194
Neurodevelopmental disorders are complex conditions that pose difficulty in the modulation of proper motor, sensory and cognitive function due to dysregulated neuronal development. Previous studies have reported that an imbalance... -
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- PRR16/Largen Induces Epithelial-Mesenchymal Transition through the Interaction with ABI2 Leading to the Activation of ABL1 Kinase
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Kang GJ, Park JH, Kim HJ, Kim EJ, Kim B, Byun HJ, Yu L, Nguyen TM, Nguyen TH, Kim KS, Huy HP, Rahman M, Kim YH, Jang JY, Park MK, Lee H, Choi CI, Lee K, Han HK, Cho J, Rho SB, Lee CH
- KMID: 2530999
- Biomol Ther.
- 2022 Jul;30(4):340-347.
- doi: 10.4062/biomolther.2022.066
Advanced or metastatic breast cancer affects multiple organs and is a leading cause of cancer-related death. Cancer metastasis is associated with epithelial-mesenchymal metastasis (EMT). However, the specific signals that induce... -
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- Benzyl Isothiocyanate-Induced Cytotoxicity via the Inhibition of Autophagy and Lysosomal Function in AGS Cells
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Po WW, Choi WS, Khing TM, Lee JY, Lee JH, Bang JS, Min YS, Jeong JH, Sohn UD
- KMID: 2531000
- Biomol Ther.
- 2022 Jul;30(4):348-359.
- doi: 10.4062/biomolther.2022.019
Gastric adenocarcinoma is among the top causes of cancer-related death and is one of the most commonly diagnosed carcinomas worldwide. Benzyl isothiocyanate (BITC) has been reported to inhibit the gastric... -
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