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Erratum to "Microfluidic System Based High Throughput Drug Screening System for Curcumin/TRAIL Combinational Chemotherapy in Human Prostate Cancer PC3 Cells" [Biomol. Ther. 22 (2014) 355-362]

An D, Kim K, Kim J

The authors request to correct the project number NRF-2013R1A1A1010734 from NRF-116436 on the 4th line of Acknowledgments section.
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Erratum to "L-Tetrahydropalmatine Ameliorates Development of Anxiety and Depression-Related Symptoms Induced by Single Prolonged Stress in Rats" [Biomol. Ther. 22 (2014) 213-222]

Lee B, Sur B, Yeom M, Shim I, Lee H, Hahm DH

In the article, incorrect images were placed in Fig. 8.
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Strain Differences in the Chronic Mild Stress Animal Model of Depression and Anxiety in Mice

Jung YH, Hong SI, Ma SX, Hwang JY, Kim JS, Lee JH, Seo JY, Lee SY, Jang CG

Chronic mild stress (CMS) has been reported to induce an anhedonic-like state in mice that resembles some of the symptoms of human depression. In the present study, we used a...
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Regulatory Role of Autophagy in Globular Adiponectin-Induced Apoptosis in Cancer Cells

Nepal S, Park PH

Adiponectin, an adipokine predominantly secreted from adipose tissue, exhibits diverse biological responses, including metabolism of glucose and lipid, and apoptosis in cancer cells. Recently, adiponectin has been shown to modulate...
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Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-alpha Release from Activated Microglia and TNF-alpha Converting Enzyme Activity

Lee EJ, Moon PG, Baek MC, Kim HS

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate cell-matrix composition and are also involved in processing various bioactive molecules such as cell-surface receptors, chemokines, and cytokines. Our group recently reported...
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Conditioned Place Preference and Self-Administration Induced by Nicotine in Adolescent and Adult Rats

Ahsan HM, de la Pena JBI, Botanas CJ, Kim HJ, Yu GY, Cheong JH

Nicotine addiction is a worldwide problem. However, previous studies characterizing the rewarding and reinforcing effects of nicotine in animal models have reported inconsistent findings. It was observed that the addictive...
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Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats

Kang JW, Lee SM

Esophageal reflux of gastric contents causes esophageal mucosal damage and inflammation. Recent studies show that oxygen-derived free radicals mediate mucosal damage in reflux esophagitis (RE). Chlorogenic acid (CGA), an ester...
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HD047703, a New Promising Anti-Diabetic Drug Candidate: In Vivo Preclinical Studies

Kim S, Kim DH, Kim YS, Ha TY, Yang J, Park SH, Jeong KW, Rhee JK

G-protein coupled receptor 119 (GPR119) has emerged as a novel target for the treatment of type 2 diabetes mellitus. GPR119 is involved in glucose-stimulated insulin secretion (GSIS) from the pancreatic...
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Resveratrol Inhibits IL-6-Induced Transcriptional Activity of AR and STAT3 in Human Prostate Cancer LNCaP-FGC Cells

Lee MH, Kundu JK, Keum YS, Cho YY, Surh YJ, Choi BY

Prostate cancer is the most frequently diagnosed cancer. Although prostate tumors respond to androgen ablation therapy at an early stage, they often acquire the potential of androgen-independent growth. Elevated transcriptional...
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The Leaves of Broussonetia kazinoki Siebold Inhibit Atopic Dermatitis-Like Response on Mite Allergen-Treated Nc/Nga Mice

Lee H, Ha H, Lee JK, Park SJ, Jeong SI, Shin HK

Broussonetia kazinoki Siebold. (B. kazinoki) has long been used in the manufacture of paper in Asian countries. Although B. kazinoki leaves (BK) have been employed in dermatological therapy, use of...
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Protective Effect of Arabinoxylan against Scopolamine-Induced Learning and Memory Impairment

Kim CY, Lee GY, Park GH, Lee J, Jang JH

The purpose of this study is to investigate the memory enhancing effect and underlying molecular mechanism of arabinoxylan (AX), a major component of dietary fiber in wheat against scopolamine (SCO)-induced...
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Dioscorea Extract (DA-9801) Modulates Markers of Peripheral Neuropathy in Type 2 Diabetic db/db Mice

Moon E, Lee SO, Kang TH, Kim HJ, Choi SZ, Son MW, Kim SY

The purpose of this study was to investigate the therapeutic effects of DA-9801, an optimized extract of Dioscorea species, on diabetic peripheral neuropathy in a type 2 diabetic animal model....
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Resveratrol-Enriched Rice Down-Regulates Melanin Synthesis in UVB-Induced Guinea Pigs Epidermal Skin Tissue

Lee TH, Seo JO, Do MH, Ji E, Baek SH, Kim SY

Synthetic compounds that are used in the clinic to regulate skin hyperpigmentation, such as arbutin, hydroquinone, and kojic acid, are only moderately effective. But, their use is limited by side...
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TI-I-174, a Synthetic Chalcone Derivative, Suppresses Nitric Oxide Production in Murine Macrophages via Heme Oxygenase-1 Induction and Inhibition of AP-1

Kim MJ, Kadayat T, Kim DE, Lee ES, Park PH

Chalcones (1,3-diaryl-2-propen-1-ones), a flavonoid subfamily, are widely known for their anti-inflammatory properties. Propenone moiety in chalcones is known to play an important role in generating biological responses by chalcones. In...
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Caenorhabditis elegans: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification

Kobet RA, Pan X, Zhang B, Pak SC, Asch AS, Lee MH

The nematode Caenorhabditis elegans (C. elegans) offers a unique opportunity for biological and basic medical researches due to its genetic tractability and well-defined developmental lineage. It also provides an exceptional...
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Effects of Atomoxetine on Hyper-Locomotive Activity of the Prenatally Valproate-Exposed Rat Offspring

Choi CS, Hong M, Kim KC, Kim JW, Yang SM, Seung H, Ko MJ, Choi DH, You JS, Shin CY, Bahn GH

A substantial proportion of patients with autism spectrum disorder (ASD) display hyperactivity as a comorbid symptom. Exposure to valproic acid (VPA) during pregnancy produces ASD-like core behavioral phenotypes as well...
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