- Rheumatoid Hand Surgery in the Era of Biologic Therapy: A Rheumatologist-oriented Overview
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Park JW, Hwang JS, Gong HS
- KMID: 2520432
- J Rheum Dis.
- 2021 Oct;28(4):192-201.
- doi: 10.4078/jrd.2021.28.4.192
Rheumatoid arthritis (RA) can cause significant hand and wrist damage and dysfunction. The aim of medical treatment is to eradicate inflammation and prevent damage to joints and soft tissues. Advances... -
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- Biologic therapies for the treatment of ankylosing spondylitis
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Ahn SM, Kim YG
- KMID: 2513066
- J Korean Med Assoc.
- 2021 Feb;64(2):116-123.
- doi: 10.5124/jkma.2021.64.2.116
Ankylosing spondylitis (AS) is a chronic inflammatory disease predominantly affecting the axial skeleton. AS treatment aims to reduce pain and inflammation and maintain functional capacity. Nonsteroidal anti-inflammatory drugs are the... -
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- Biologic therapies for the treatment of systemic lupus erythematosus
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Park SH
- KMID: 2513065
- J Korean Med Assoc.
- 2021 Feb;64(2):109-115.
- doi: 10.5124/jkma.2021.64.2.109
Systemic lupus erythematosus is a typical autoimmune disease with a complex etiology, including the interaction of genetic/epigenetic factors and environmental and hormonal factors with innate immune cells or B/T lymphocytes.... -
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- Biologics for the Management of Inflammatory Bowel Disease: A Review in Tuberculosis-Endemic Countries
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Banerjee R, Raja Ali RA, Wei SC, Adsul S
- KMID: 2508688
- Gut Liver.
- 2020 Nov;14(6):685-698.
- doi: 10.5009/gnl19209
The advent of biologics and biologic therapy has transformed the management of inflammatory bowel disease (IBD) with enhanced early and adequate responses to treatment, fewer hospitalizations, a reduced need for... -
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- Biologic agents for asthma treatment
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Kim SR, Lee JH
- KMID: 2434124
- Allergy Asthma Respir Dis.
- 2019 Jan;7(1):3-12.
- doi: 10.4168/aard.2019.7.1.3
Most treatment strategies for asthma currently include inhaled corticosteroids, with the addition of long-acting beta-2-agonists or leukotriene modifiers, if necessary. However, some patients may not respond to conventional treatment. A... -
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- Fecal microbiota transplantation for refractory Crohn's disease
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Bak SH, Choi HH, Lee J, Kim MH, Lee YH, Kim JS, Cho YS
- KMID: 2425168
- Intest Res.
- 2017 Apr;15(2):244-248.
- doi: 10.5217/ir.2017.15.2.244
Approximately one-third of patients with Crohn's disease do not respond to conventional treatments, and some experience significant adverse effects, such as serious infections and lymphoma, and many patients require surgery... -
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- Tumor Necrosis Factor Blockade Stimulates Circulating Osteoblastic Lineage Cells Activity while Reducing Circulating Osteoclasts
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Lim MJ, Kwon SR, Jung KH, Park W
- KMID: 2364689
- J Rheum Dis.
- 2016 Dec;23(6):356-362.
- doi: 10.4078/jrd.2016.23.6.356
OBJECTIVE: This study examines the effects of tumor necrosis factor (TNF) blockade on markers of bone metabolism in peripheral blood from active rheumatoid arthritis (RA) patients. METHODS: Eighteen patients (16 women,... -
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- Biologic Agents in Rheumatic Diseases
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Hong MJ, Yoo WH
- KMID: 2263548
- Korean J Med.
- 2012 May;82(5):549-561.
During the past three decades the treatment in rheumatology was revolutionized by the introduction of disease-modifying anti-rheumatic drugs. Advances in our understanding of the pathogenesis of rheumatic diseases have led... -
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- Recent Advances in Mechanisms and Treatments of Airway Remodeling in Asthma: A Message from the Bench Side to the Clinic
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Cho JY
- KMID: 1729239
- Korean J Intern Med.
- 2011 Dec;26(4):367-383.
- doi: 10.3904/kjim.2011.26.4.367
Airway remodeling in asthma is a result of persistent inflammation and epithelial damage in response to repetitive injury. Recent studies have identified several important mediators associated with airway remodeling in... -
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- Anti-HER2/neu Peptide Producing Vector System for Biologic Therapy - Is It Possible to Mass-produce the Peptide?
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Park BW, Kim KS, Heo MK, Lee KS, Kim EK, Kim KS
- KMID: 1719070
- Yonsei Med J.
- 2003 Feb;44(1):58-64.
- doi: 10.3349/ymj.2003.44.1.58
A humanized monoclonal antibody against HER2 has been using in a clinical setting and has been shown to possess therapeutic properties. A mimetic peptide against HER2 was also reported to... -
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