- Erlotinib (Tarceva(R)) Induced Hair Abnormalities
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Choi CM, Lew BL, Sim WY
- KMID: 2247599
- Korean J Dermatol.
- 2011 Apr;49(4):382-384.
Erlotinib is a low-molecular-weight quinazoline derivative that inhibits the activation of epidermal growth factor receptor (EGFR) tyrosine kinase through competitive binding of the adenosine triphosphate binding domain of the receptor.... -
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- Development of Competitive ELISA for Detection of Avian Metapneumovirus Antibodies in Chicken
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Choi KS, Kim JW, Lee EK, Jeon WJ, Park MJ, Lyoo YN, Kwon JH
- KMID: 2055050
- J Bacteriol Virol.
- 2010 Sep;40(3):131-143.
- doi: 10.4167/jbv.2010.40.3.131
Avian metapneumovirus (aMPV) causes an acute and highly contagious upper respiratory tract infection in turkeys and chickens. In this study, a competitive ELISA (C-ELISA) was developed for the detection of... -
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- The Oxidation Process of Red Blood Cells and the Molecules Involved in their Binding to Macrophage
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Ko HS, Kim CW, Choi SH, Lee KJ, Kim SW, Kim TH, Kim CJ, Ryu WS
- KMID: 2227251
- Korean Circ J.
- 2003 Dec;33(12):1174-1181.
- doi: 10.4070/kcj.2003.33.12.1174
BACKGROUND AND OBJECTIVES: Controversy exists about the characteristics of the lipid-oxidizing process, and the molecules in oxidized lipids that are involved in the binding and uptake to macrophages, in atherosclerosis.... -
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- A new member of alpha 1-adrenoceptor-coupled G alpha h (transglutaminase II) family in pig heart: purification and characterization
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Yoo SM, Jeong HS, Han KJ, Cho SH, Lee HS, Yun HY, Kwon NS, Baek KJ
- KMID: 754992
- Exp Mol Med.
- 1998 Jun;30(2):81-86.
We previously reported an identification of a 77-kDa GTP-binding protein that co-purified with the alpha 1-adrenoceptor following ternary complex formation. In the present paper, we report on the purification and characterization of... -
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- Characterization of Antigenic Sites on the Rinderpest Virus N Protein Uusing Monoclonal Antibodies
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Choi KS, Nah JJ, Ko YJ, Choi CU, Kim JH, Kang SY, Joo YS
- KMID: 1099822
- J Vet Sci.
- 2003 Apr;4(1):57-65.
The N protein of the rinderpest virus (RPV) was analyzed topologically and antigenically by using anti-N monoclonal antibodies (Mabs). Ten Mabs were raised against the N protein of the RPV.... -
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- Functional Role of Serine Residues of Transmembrane Dopamin VII in Signal Transduction of CB2 Cannabinoid Receptor
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Rhee MH
- KMID: 1095120
- J Vet Sci.
- 2002 Sep;3(3):185-191.
Using site-directed mutagenesis technique, I have replaced serine 285 and serine 292 with the alanine, and assessed the binding of agonist and signaling such as the inhibition of adenylyl cyclase... -
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- Neurotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells
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Kim SY, Yang JH
- KMID: 1033102
- Exp Mol Med.
- 2005 Feb;37(1):58-64.
An environmental pollutant, tetrachloro dibenzo dioxin (TCDD) is known to illicit the cognitive disability and motor dysfunction in the developing brain. TCDD induced effects leading to neurodevelopmental and neurobehavioral deficit... -
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- Negative correlation between the conversion of thyrotropin receptor-bound blocking type thyrotropin receptor antibody to the stimulating type by anti-human IgG antibodies and the biological activity of blocking type thyrotropin receptor antibody
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Cho BY, Shong MH, Chung JH, Lee HK, Koh CS, Min HK
- KMID: 1422003
- J Korean Med Sci.
- 1993 Oct;8(5):355-360.
- doi: 10.3346/jkms.1993.8.5.355
It has been reported that receptor-bound blocking type TSH receptor antibody (TRAb) can be converted to the stimulating type by anti-human IgG antibodies. To evaluate the relationship between the conversion... -
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- Structural basis for inhibition of protein tyrosine phosphatases by Keggin compounds phosphomolybdate and phosphotungstate.
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Heo YS, Ryu JM, Park SM, Park JH, Lee HC, Hwang KY, Kim JS
- KMID: 1380229
- Exp Mol Med.
- 2002 Jul;34(3):211-223.
Protein-tyrosine phosphatases (PTPs) constitute a family of receptor-like, and cytoplasmic enzymes, which catalyze the dephosphorylation of phosphotyrosine residues in a variety of receptors and signaling molecules. Together with protein tyrosine... -
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- Serodiagnosis of human sparganosis by a monoclonal antibody-based competition ELISA
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Yeo IS, Yong TS, Im KI
- KMID: 1381216
- Yonsei Med J.
- 1994 Mar;35(1):43-48.
- doi: 10.3349/ymj.1994.35.1.43
Competition ELISA test using sparganum specific monoclonal antibodies (Mab) was investigated to improve the diagnostic specificity of sparganosis. By cell fusion, one hybridoma clone secreting anti-sparganum specific Mab was selected... -
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- Platelet agglutinating protein (PAP p37) from a patient with thrombotic thrombocytopenic purpura is identical with prethrombin 2
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Jin JY, Park SJ, Lee JW, Kim SH
- KMID: 1889651
- Korean J Med.
- 2001 Apr;60(4):373-382.
BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is characterized by widespread platelet thrombi with little fibrin in the arterioles and capillaries. Unusually large or multimeric von Willebrand factor (vWF) and one or... -
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- SR144528 as Inverse Agonist of CB2 Cannabinoid Receptor
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Rhee MH, Kim SK
- KMID: 1095119
- J Vet Sci.
- 2002 Sep;3(3):179-184.
It is now well established that several G protein- coupled receptors can signal without agonist stimulation (constitutive receptors). Inverse agonists have been shown to inhibit the activity of such constitutive... -
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- Human beta-defensin 2 is induced by interleukin-1b in the cornealepithelial cells
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Shin JS, Kim CW, Kwon YS, Kim JC
- KMID: 1097101
- Exp Mol Med.
- 2004 Jun;36(3):204-210.
Mammalian epithelia produce the various antimicrobial peptides against the bacterial or viral infection, thereby acting as the active immune modulators in the innate immunity. In this study, we examined the... -
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