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High pressure liquid chromatographic analysis of conjugated bile acids in gallbladder bile of Korean adults

Yoon YB, Kim YT, Kim CY

  • KMID: 1685267
  • Korean J Gastroenterol.
  • 1991 Feb;23(1):145-150.
No abstract available.
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Effect of Bile Acids on Biliary Excretion of Cholesterol in Rabbits

Hong SS, Kim KH, Kim WJ

  • KMID: 2439778
  • Yonsei Med J.
  • 1973 Dec;14(1):109-115.
The effects of cholic acid and eight related cholanic acid analogs on bile flow and biliary excretion of bile salts and cholesterol were studied in rabbits. Bile acids were infused...
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Pathophysiology of gallstone

Joo KR

  • KMID: 2258709
  • Korean J Med.
  • 2008 Dec;75(6):607-615.
Gallstones form as the culmination of a complex series of events that results in precipitation of insoluble substances including cholesterol or bilirubin in the gallbladder. Bile formation is essential for...
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Bile Acids and the Metabolic Disorders

Roh JH, Yoon JH

Bile acids are major constituents of bile and known to help absorb dietary fat and fat-soluble vitamins in the gastrointestinal tract. In the past few decades, many studies have shown...
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Understanding Bile Acid Signaling in Diabetes: From Pathophysiology to Therapeutic Targets

Ferrell JM, Chiang JY

Diabetes and obesity have reached an epidemic status worldwide. Diabetes increases the risk for cardiovascular disease and non-alcoholic fatty liver disease. Primary bile acids are synthesized in hepatocytes and are...
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Asymptomatic Accessory Bile Duct Draining into the Stomach

Do MY, Park KS, Kim ES, Cho KB, Kim MJ

No abstract available.
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Biliary Bile Acid Analysis in the Patients with Bile Duct Cancer

Lee JH, Park YH, Seo JH, Chung JB, Lee SJ, Chung JP, Song SY, Kang JK

  • KMID: 2304632
  • Korean J Gastroenterol.
  • 2000 Jan;35(1):103-110.
BACKGROUND/AIMS: Bile acids including deoxycholic acid (DCA) have been known as carcinogenic on human colonic mucosa. However, limited data on changes of bile acid composition in the patients with bile duct cancer are...
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The Analysis of Gallbladder Bile Acid Concentration in Patients with Colorectal Cancer

Cho YJ, Hahm JS, Choi HS, Lee YW, Jeon YC, Sohn JH, Yoon BC, Lee MH, Lee DH, Kee CS, Park KN, Park YS, Jun KY

  • KMID: 1571064
  • Korean J Gastroenterol.
  • 2000 Feb;35(2):233-241.
BACKGROUND/AIMS: Changes of bile acid concentration may play an important role in the carcinogenesis of colorectal cancer. We intended to assess the difference in bile acid concentrations between patients with...
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Serum Fat Soluble Vitamins in Bile Duct Ligated Rats

Sim JG, O MH, Kim KH

  • KMID: 2275100
  • Korean J Pediatr Gastroenterol Nutr.
  • 1999 Mar;2(1):59-64.
PURPOSE: The aims of this study are to measure the serum levels of fat soluble vitamins (vitamin A and D) from bile duct ligated rats, and to evaluate the effect...
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Bile acid modulation of gastroinstinal smooth muscle contraction and ionic currents

Lee HK, Lee KH

  • KMID: 1917027
  • Korean J Physiol Pharmacol.
  • 2000 Aug;4(4):333-338.
We have examined whether bile acids can affect the electrical and mechanical activities of circular smooth muscle of canine colon and ileum, using isometric tension measurement or patch clamp technique. It was found...
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Crosstalk between FXR and TGR5 controls glucagon-like peptide 1 secretion to maintain glycemic homeostasis

Kim H, Fang S

Though bile acids have been well known as digestive juice, recent studies have demonstrated that bile acids bind to their endogenous receptors, including Farnesoid X receptor (FXR) and G protein-coupled...
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The Effect of Microbiota on Colon Carcinogenesis

Yoon K, Kim N

Although genetic background is known to contribute to colon carcinogenesis, the exact etiology of the disease remains elusive. The organ’s extensive interaction with microbes necessitated research on the role of...
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Toxicity of Bile Acids on Colon Cancer Cell Lines

Park DK, Shin JH, Jun HJ, Kim KJ, Lee CY

  • KMID: 2175280
  • J Korean Cancer Assoc.
  • 1999 Feb;31(1):126-133.
PURPOSE: Cytotoxicity of the bile acids on colon cancer cell lines was studied to know which bile acid was most cytotoxic to colonic mucosal epithelium. We performed agarose gel electrophoresis...
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Induction of apoptosis by bile acids in HepG2 human hepatocellular carcinoma cells

Baek JH, Kim JA, Kang CM, Lee YS, Kim KW

  • KMID: 2285165
  • Korean J Physiol Pharmacol.
  • 1997 Feb;1(1):107-115.
We studied the effects of bile acids on the induction of apoptosis in HepG2 human hepatocellular carcinoma cells. Treatment with either ursodeoxycholic acid (UDCA) or lithocholic acid (LCA) resulted in a dose- and...
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What's New? Oral Dissolution Therapy for Gallstone

Lee DK

  • KMID: 2168081
  • Hanyang Med Rev.
  • 2007 Feb;27(1):35-41.
The standard treatment of the gallbladder stone is laparoscopic cholecystectomy, making gallstone disease very costly digestive disorder in many countries. Despite a rapid convalescence, the procedure is not devoid of...
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Effect of Bile on the Blood Coagulation

Chung SC, Kim YC, Hong SK, Lee PH

The bile samples were obtained from the gall bladder as well as from the common bile duct of the human and the dog, and the effect on the coagulation of...
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Bile Acid Receptor Farnesoid X Receptor: A Novel Therapeutic Target for Metabolic Diseases

Fang S

Bile acid has been well known to serve as a hormone in regulating transcriptional activity of Farnesoid X receptor (FXR), an endogenous bile acid nuclear receptor. Moreover, bile acid regulates...
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Roles of Small Intestinal Transit Time in the Pathogenesis of Cholesterol Gallstones

Lee JW, Kim IH, Kim SH, Kwon KS, Choi W, Lee DH, Cho HG, Kim PS, Kim HG, Shin YW, Kim YS, Lee KY

  • KMID: 1548531
  • Korean J Gastroenterol.
  • 1999 Nov;34(5):660-666.
BACKGROUND/AIMS: Gallbladder motility and small intestinal transit govern the cycling frequency of bile salts and their hepatic secretion rate. Therefore, the impaired gallbladder motility and the delayed intestinal transit contribute...
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Implications for Farnesoid X Receptor Signaling on Bile Acid Metabolism as a Potential Therapeutic Strategy for Nonalcoholic Fatty Liver Disease

Yang H, Park CY

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in both developed and developing countries and is an important risk factor for both hepatic and cardiometabolic mortality....
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The Composition of Modified BHI Medium for Optimal Growth of Malassezia spp.

Yang NW

BACKGROUND: There are several media for culture of Malassezia spp., such as Leeming & Notman (LN) medium, modified Leeming & Notman (mLN) medium, Dixon's medium and modified Dixon's medium etc....
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