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Comparison of normal saline solution with low-chloride solutions in renal transplants: a meta-analysis

Jahangir A, Sahra S, Niazi MRK, Siddiqui FS, Anwar MY, Jahangir A, El-Charabaty EJ

Background: Normal saline solution (NSS) has been the fluid of choice for renal transplant patients, but it can lead to hyperchloremic acidosis and hyperkalemia. This study was performed to compare...
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Epidermal Necrosis of Forearm and Wrist due to Extravasation of Sodium Bicarbonate and Application of Epidermal Growth Factor for Therapy in Extremely Low Birth Weight Infant

Cho HK, Yang HJ, Cho JY, Jung HW, Choi YS

Extravasation occurs when an intravenous drug is inadvertently administered into the perivascular space or subcutaneous tissue. This can have various consequences, from local irritation to severe tissue loss. Extravasation occur...
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Relationship between serum total carbon dioxide concentration and bicarbonate concentration in patients undergoing hemodialysis

Hirai K, Ookawara S, Morino J, Minato S, Kaneko S, Yanai K, Ishii H, Matsuyama M, Kitano T, Shindo M, Miyazawa H, Ito K, Ueda Y, Watano T, Fujino S, Omoto K, Morishita Y

Background: Few studies have investigated the relationship between serum total carbon dioxide (CO2) concentration and bicarbonate ion (HCO3-) concentration in patients undergoing hemodialysis. We determined the agreement and discrepancy between...
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Cystic fibrosis lung disease: Current perspectives

Jung JA

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). These mutations alter the synthesis, processing, function, or...
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Approximation of bicarbonate concentration using serum total carbon dioxide concentration in patients with non-dialysis chronic kidney disease

Hirai K, Minato S, Kaneko S, Yanai K, Ishii H, Kitano T, Shindo M, Miyazawa H, Ito K, Ueda Y, Kaku Y, Hoshino T, Watano T, Fujino S, Ookawara S, Omoto K, Morishita

BACKGROUND: We investigated the relationship between serum total carbon dioxide (CO₂) and bicarbonate ion (HCO₃⁻) concentrations in pre-dialysis chronic kidney disease (CKD) patients and devised a formula for predicting low...
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The Clinical Efficacy of a Pure Alginate Formulation (Lamina G) for Controlling Symptoms in Individuals with Reflux Symptoms: A Randomized Clinical Study

Kim JH, Lee YC, Kim EH, Park JC, Shin SK, Lee SK, Jung DH, Park JJ, Youn YH, Park H

BACKGROUND/AIMS: Bicarbonate-containing alginate formulations are reported to be effective for controlling reflux symptoms. However, the efficacy of Lamina G alginate without gas production has not been reported. The aim is...
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Efficacy of sodium bicarbonate buffered versus non-buffered lidocaine with epinephrine in inferior alveolar nerve block: A meta-analysis

Guo J, Yin K, Roges R, Enciso R

INTRODUCTION: This systematic review evaluated the use of buffered versus non-buffered lidocaine to increase the efficacy of inferior alveolar nerve block (IANB). MATERIALS AND METHODS: Randomized, double-blinded studies from PubMed, Web...
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Delayed Recovery of Motor Block Following Radiofrequency Ablation of Varicose Veins with Femoral Nerve Block and Tumescent Anesthesia

Jun MR, Kim YE, Yoon SC, Kim MG

Femoral nerve block with tumescent anesthesia is used to perform the radiofrequency ablation of varicose veins. The surgery can be done as day-case. But if recovery from motor block is...
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The role of renal proximal tubule transport in the regulation of blood pressure

Horita S, Nakamura M, Suzuki M, Satoh N, Suzuki A, Homma Y, Nangaku M

The electrogenic sodium/bicarbonate cotransporter 1 (NBCe1) on the basolateral side of the renal proximal tubule plays a pivotal role in systemic acid-base homeostasis. Mutations in the gene encoding NBCe1 cause...
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The impact of high serum bicarbonate levels on mortality in hemodialysis patients

Chang KY, Kim HW, Kim WJ, Kim YK, Kim SH, Song HC, Kim YO, Jin DC, Choi EJ, Yang CW, Kim YL, Kim NH, Kang SW, Kim YS, Kim YS

BACKGROUND/AIMS: The optimal serum bicarbonate level is controversial for patients who are undergoing hemodialysis (HD). In this study, we analyzed the impact of serum bicarbonate levels on mortality among HD...
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Effectiveness of a baking soda dentifrice on gingivitis and tooth surface

Cho HJ, Paik DI, Han DH

OBJECTIVES: To evaluate the effectiveness of sodium bicarbonate dentifrices in reducing gingivitis and tooth abrasiveness and improving tooth gloss, as compared to a conventional fluoride/silica-containing dentifrice. METHODS: In this double-blinded, randomized...
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Alkali Therapy Attenuates the Progression of Kidney Injury via Na/H Exchanger Inhibition in 5/6 Nephrectomized Rats

Kim S, Lee J, Heo NJ, Lee JW, Han JS

Metabolic acidosis is a cause of renal disease progression, and alkali therapy ameliorates its progression. However, there are few reports on the role of renal acid-base transporters during alkali therapy....
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Effect of Bicarbonate Supplementation on Renal Function and Nutritional Indices in Predialysis Advanced Chronic Kidney Disease

Jeong J, Kwon SK, Kim HY

Current practice guidelines recommend alkali therapy in patients with chronic kidney disease (CKD) and metabolic acidosis to prevent complications. This study aims to investigate the effect of oral sodium bicarbonate...
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Sodium Bicarbonate Solution versus Chlorhexidine Mouthwash in Oral Care of Acute Leukemia Patients Undergoing Induction Chemotherapy: A Randomized Controlled Trial

Choi SE, Kim HS

  • KMID: 2268165
  • Asian Nurs Res.
  • 2012 Jun;6(2):60-66.
PURPOSE: The objective of this study was to compare the effectiveness of sodium bicarbonate (SB) solution with chlorhexidine (CHX) mouthwash in oral care of acute leukemia patients under induction chemotherapy. METHODS:...
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Intravenous Sodium Bicarbonate and Oral N-acetylcysteine for the Prevention of Contrast-Induced Nephropathy

Koo TY, Kim JH, Lee J, Shin JH, Kim KS, Choi BY, Park JS, Lee CH, Kang CM, Kim GH

  • KMID: 2258953
  • Korean J Med.
  • 2011 May;80(5):537-545.
BACKGROUND/AIMS: The value of hydration with sodium bicarbonate and N-acetylcysteine (NAC) in the prevention of radiocontrast-induced nephropathy is questionable. This study investigated whether sodium bicarbonate hydration with or without NAC...
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Role of Intravenous Sodium Bicarbonate and Oral N-acetylcysteine in Radiocontrast-Induced Nephropathy

Oh DJ

  • KMID: 2258952
  • Korean J Med.
  • 2011 May;80(5):534-536.
No abstract available.
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A Case of Electrocardiographic and Mental Change in a Patient with a Diphenhydramine Overdose

Park CS, Kang IG, Ryu HS, Park SS, Lee MJ, Jeong WJ

  • KMID: 2332762
  • J Korean Soc Emerg Med.
  • 2010 Jun;21(3):405-411.
The antihistaminic drug diphenhydramine is mainly used as a sedative, hypnotic and antiemetic. In many countries it is available over-the-counter, very common, and generally regarded as a harmless drug. However,...
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Molecular Approach for Distal Renal Tubular Acidosis Associated AE1 Mutations

Vasuvattakul S

The molecular approaches to distal renal tubular acidosis (dRTA) associated AE1 mutations lead us to understand the genetic and pathophysiological aspects of the acidification defects. An unanticipated high value of...
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Insulin Treatment of Shock Induced by Acute Propafenone Toxicity Refractory to Sodium Bicarbonate Administration

Yi HY, Lee JY

  • KMID: 2332856
  • J Korean Soc Emerg Med.
  • 2010 Dec;21(6):906-909.
Propafenone is a Class Ic antidysrhythmic agent, used in the management of atrial fibrillation. This is also a calcium channel and a weak beta blocker. The conventional therapy of hypotension...
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Altered Renal Expression of Acid-base Transporters in Rats with Glycerol-induced Tubular Injury

Ma SK, Bae EH, Lee J, Kim SW

The present study aimed to investigate the altered regulation of renal tubular acid-base transporters in rats with glycerol-induced tubular injury. Male Sprague-Dawley rats were used. Rats were injected with 50%...
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