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Evaluation of PCR-SSCP vs. PCR - Sequence Analysis for Detecting Rifampicin Resistance of Mycobacterium tuberculosis Clinical Isolates

Cho SN, Kim JD, Lee JH, Lee HY, Bang HE, Bae GH, Kim SJ

  • KMID: 1943435
  • J Korean Soc Microbiol.
  • 1997 Dec;32(6):625-632.
In the present study, we made an attempt to compare polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) with PCR-direct sequence analysis for their accuracy and sensitivity in detecting resistance to...
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Mutations in the embB Locus among Korean Clinical Isolates of Mycobacterium tuberculosis Resistant to Ethambutol

Lee HY, Myoung HJ, Bang HE, Bai GH, Kim SJ, Kim JD, Cho SN

Resistance of Mycobacterium tuberculosis to ethambutol (EMB) has been assigned to an operon, embCAB, which has been proposed to be a structural gene for mycobacterial arabinosyl transferases. Recently, genetic events...
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