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Msi1-Like (MSIL) Proteins in Fungi

Yang DH, Maeng S, Bahn YS

  • KMID: 2312679
  • Mycobiology.
  • 2013 Mar;41(1):1-12.
Msi1-like (MSIL) proteins, which are eukaryote-specific and contain a series of WD40 repeats, have pleiotropic roles in chromatin assembly, DNA damage repair, and regulation of nutrient/stress-sensing signaling pathways. In the...
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Functional Characterization of cAMP-Regulated Gene, CAR1, in Cryptococcus neoformans

Jung KW, Maeng S, Bahn YS

  • KMID: 2312560
  • Mycobiology.
  • 2010 Mar;38(1):26-32.
The cyclic AMP (cAMP) pathway plays a major role in growth, sexual differentiation, and virulence factor synthesis of pathogenic fungi. In Cryptococcus neoformans, perturbation of the cAMP pathway, such as...
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A Ferroxidase, Cfo1, Regulates Diverse Environmental Stress Responses of Cryptococcus neoformans through the HOG Pathway

Lee KT, Lee JW, Lee D, Jung WH, Bahn YS

  • KMID: 2312738
  • Mycobiology.
  • 2014 Jun;42(2):152-157.
The iron uptake and utilization pathways play a critical role in allowing human pathogens, including Cryptococcus neoformans, the causative agent of fatal meningoencephalitis, to survive within the mammalian body by...
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A Nudix Hydrolase Protein, Ysa1, Regulates Oxidative Stress Response and Antifungal Drug Susceptibility in Cryptococcus neoformans

Lee KT, Kwon H, Lee D, Bahn YS

  • KMID: 2312723
  • Mycobiology.
  • 2014 Mar;42(1):52-58.
A nucleoside diphosphate-linked moiety X (Nudix) hydrolase-like gene, YSA1, has been identified as one of the gromwell plant extract-responsive genes in Cryptococcus neoformans. Ysa1 is known to control intracellular concentrations...
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The Stress-Activated Signaling (SAS) Pathways of a Human Fungal Pathogen, Cryptococcus neoformans

Jung KW, Bahn YS

Cryptococcus neoformans is a basidiomycete human fungal pathogen that causes meningoencephalitis in both immunocompromised and immunocompetent individuals. The ability to sense and respond to diverse extracellular signals is essential for...
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