- p15(Ink4b) Loss of Expression by Promoter Hypermethylation Adds to Leukemogenesis and Confers a Poor Prognosis in Acute Promyelocytic Leukemia Patients
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Baba SM, Azad NA, Shah ZA, Dil-Afroze , Pandith AA, Jan A, Aziz SA
- KMID: 2388324
- Cancer Res Treat.
- 2017 Jul;49(3):790-797.
- doi: 10.4143/crt.2016.108
PURPOSE: The p15(Ink4b) gene exerts its influence as an inhibitor of cyclin-dependent kinases and is frequently associated with hematological malignancies. Inactivation of this gene through DNA methylation has been found... -
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- Long-term Safety and Efficacy of Esketamine Nasal Spray Plus an Oral Antidepressant in Patients with Treatment-resistant Depression– an Asian Sub-group Analysis from the SUSTAIN-2 Study
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Jeon HJ, Ju PC, Sulaiman AH, Aziz SA, Paik JW, Tan W, Bai D, Li CT
- KMID: 2526849
- Clin Psychopharmacol Neurosci.
- 2022 Feb;20(1):70-86.
- doi: 10.9758/cpn.2022.20.1.70
Objective: To evaluate the long-term safety and efficacy of intranasal esketamine in patients with treatment-resistant depression from the Asian subgroup of the SUSTAIN-2 study. Methods: SUSTAIN-2 was a phase 3, open-label,... -
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