- p15(Ink4b) Loss of Expression by Promoter Hypermethylation Adds to Leukemogenesis and Confers a Poor Prognosis in Acute Promyelocytic Leukemia Patients
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Baba SM, Azad NA, Shah ZA, Dil-Afroze , Pandith AA, Jan A, Aziz SA
- KMID: 2388324
- Cancer Res Treat.
- 2017 Jul;49(3):790-797.
- doi: 10.4143/crt.2016.108
PURPOSE: The p15(Ink4b) gene exerts its influence as an inhibitor of cyclin-dependent kinases and is frequently associated with hematological malignancies. Inactivation of this gene through DNA methylation has been found... -
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