- Synergistic Effect of Trabectedin and Olaparib Combination Regimen in Breast Cancer Cell Lines
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Avila-Arroyo S, Nunez GS, Garcia-Fernandez LF, Galmarini
- KMID: 2176281
- J Breast Cancer.
- 2015 Dec;18(4):329-338.
- doi: 10.4048/jbc.2015.18.4.329
PURPOSE: Trabectedin induces synthetic lethality in tumor cells carrying defects in homologous recombinant DNA repair. We evaluated the effect of concomitant inhibition of nucleotide-excision repair and poly (ADP-ribose) polymerase (PARP)... -
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