- Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic beta-cells
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Quan W, Lim YM, Lee MS
- KMID: 1120126
- Exp Mol Med.
- 2012 Feb;44(2):81-88.
- doi: 10.3858/emm.2012.44.2.030
Type 2 diabetes mellitus is characterized by insulin resistance and failure of pancreatic beta-cells producing insulin. Autophagy plays a crucial role in cellular homeostasis through degradation and recycling of organelles... -
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- Molecules and their functions in autophagy
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Pyo JO, Nah J, Jung YK
- KMID: 1120125
- Exp Mol Med.
- 2012 Feb;44(2):73-80.
- doi: 10.3858/emm.2012.44.2.029
Autophagy is a self-degradation system of cellular components through an autophagosomal-lysosomal pathway. Over the last 15 yr, yeast genetic screens led to the identification of a number of genes involved... -
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