- Epigallocatechin-3-gallate inhibits paracrine and autocrine hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion
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Kwak IH, Shin YH, Kim M, Cha HY, Nam HJ, Lee BS, Chaudhary , Pai KS, Lee JH
- KMID: 1097268
- Exp Mol Med.
- 2011 Feb;43(2):111-120.
- doi: 10.3858/emm.2011.43.2.013
Aberrant activation of hepatocyte growth factor/scatter factor (HGF/SF) and its receptor, Met, is involved in the development and progression of many human cancers. In the cell-based screening assay, (-)epigallocatechin-3-gallate (EGCG)... -
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- ATP released from beta-amyloid-stimulated microglia induces reactive oxygen species production in an autocrine fashion
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Kim SY, Moon JH, Lee HG, Kim SU, Lee YB
- KMID: 1091077
- Exp Mol Med.
- 2007 Dec;39(6):820-827.
Present study demonstrated that fibrillar beta-amyloid peptide (fAbeta(1-42)) induced ATP release, which in turn activated NADPH oxidase via the P2X(7) receptor (P2X(7)R). Reactive oxygen species (ROS) production in fAbeta(1-42)-treated microglia... -
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