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Autism-like Behaviors in Male Juvenile Offspring after Maternal Glyphosate Exposure

Pu Y, Ma L, Shan J, Wan X, Hammock BD, Hashimoto K

Objective: Exposure to the herbicide glyphosate during pregnancy and lactation may increase the risk for autism spectrum disorder (ASD) in offspring. Recently, we reported that maternal exposure of formulated glyphosate...
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Hypertension Induced by Aripiprazole Use in an Autistic Child Patient

Uzun AD, Sapmaz SY, Öztürk M, Kandemir H

Atypical antipsychotics in children and adolescents are widely used for aggression, emotional variability and psychosis treatment. Aripiprazole is also an atypical antipsychotic that increasingly used in children and adolescents with...
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Low Retinal Dehydrogenase 1 (RALDH1) Level in Prepubertal Boys with Autism Spectrum Disorder: A Possible Link to Dopamine Dysfunction?

Pavăl D, Rad F, Rusu R, Niculae AS, Colosi HA, Dobrescu I, Dronca E

OBJECTIVE: Retinal dehydrogenase 1 (RALDH1) is a cytosolic enzyme which acts both as a source of retinoic acid (RA) and as a detoxification enzyme. RALDH1 has key functions in the...
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Progressive Encephalomyelitis with Rigidity and Myoclonus in an Intellectually Disabled Patient Mimicking Neuroleptic Malignant Syndrome

Xu Z, Prasad K, Yeo T

We present a case of 32-year-old male with profound mental retardation and autism spectrum disorder who had presented with seizures, rigidity and elevated creatine kinase and was initially diagnosed as...
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Valproic Acid Exposure during Early Postnatal Gliogenesis Leads to Autistic-like Behaviors in Rats

Mony TJ, Lee JW, Dreyfus C, DiCicco-Bloom E, Lee HJ

OBJECTIVE: We reported that postnatal exposure of rats to valproic acid (VPA) stimulated proliferation of glial precursors during cortical gliogenesis. However, there are no reports whether enhanced postnatal gliogenesis affects...
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Psychological Assessment in Neurodevelopmental Disorders

Oh MY

Neurodevelopmental disorders are characterized by impaired development that causes adjustment problems. The spectrum of developmental impairment varies and includes intellectual disabilities, communication and social interaction challenges, and attention and executive...
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A Short Review on the Current Understanding of Autism Spectrum Disorders

Park HR, Lee JM, Moon HE, Lee DS, Kim BN, Kim J, Kim DG, Paek SH

Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures...
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Differences in Life Transition Process of Parents Caring for Children with Autism: Based on the Socio-Demographic Characteristics

Lee AR, Hong SW

PURPOSE: This study was done to identify differences in the life transition process of parents caring for children with autism according to parents' socio-demographic characteristics. METHODS: Participants were 194 parents caring...
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The role of de novo variants in complex and rare diseases pathogenesis

Rahman M, Lee W, Choi M

De novo variants (DNVs) can arise during parental germ cell formation, fertilization, and the processes of embryogenesis. It is estimated that each individual carries 60-100 such spontaneous variants in the...
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Sedation using 5% lidocaine patches, midazolam and propofol in a combative, obese adolescent with severe autistic disorder undergoing brain magnetic resonance imaging: a case report

Seo KH, Jung HS, Kang EG, Kim CJ, Rhee HY, Jeon YS

We present a 17-year-old man who underwent brain magnetic resonance imaging and laboratory exams for uncontrolled seizure. Patients with an autistic disorder require deep sedation or, occasionally, general anesthesia even...
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Construct Validity of the Life Transition Scale for Parents of Children with Autism

Lee AR, Hong SW, Ju SJ

PURPOSE: The study was done to identify the construct validity and reliability of the life transition scale (LTS) for parents who have children with autism. METHODS: Exploratory factor analysis (EFA) and...
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A Preliminary Study for the Rating of Pharmacological Effect with Aberrant Behavior Checklist in Children with Autistic Disorder

Moon DS, Chung US, Jung SH, Cho AR, Bahn GH

  • KMID: 2291626
  • J Korean Acad Child Adolesc Psychiatry.
  • 2013 Sep;24(3):164-169.
OBJECTIVES: We assessed the availability of Aberrant Behavior Checklist (ABC) for the evaluation of the pharmacological effect in autistic disorder. METHODS: A retrospective review of the medical records of 27 children...
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Development of a Scale to Measure Life Transition Process in Parents of Children with Autism

Lee AR, Hong SW, Ju SJ

PURPOSE: The purpose of this research was to develop a scale to measure the life transition process of parents of children with autism, against the backdrop of a lack of...
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Life Transition of Mothers of Children with Autism

Lee AR, Hong SW, Kim JS, Ju SJ

PURPOSE: While there are a number of studies on children with disabilities, there have been few studies on mothers of children with autism. The purpose of this study was to...
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Assessment of Neurologic Problems in Autism Spectrum Disorder and ADHD

Sim JY, Son JW, Kim YD, Kim WS

  • KMID: 2176839
  • J Korean Child Neurol Soc.
  • 2010 Nov;18(2):284-291.
PURPOSE: Autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are neurodevelopmental disorders. previous report have examined the neurologic problems both in ASD and ADHD. METHODS: We studied 49 children with...
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Regional Cerebral Perfusion Abnormalities in Autistic Disorder: Statistical Parametric Mapping Analysis

Kim SJ, Kim BN, Cho SC, Kang JW, Kim JW, Shin MS, Cheong KM, Kim HW

  • KMID: 1983121
  • J Korean Acad Child Adolesc Psychiatry.
  • 2009 Oct;20(3):122-128.
OBJECTIVES: Autism is a well-known psychiatric disorder that is presumed to have a neural basis. To investigate the underlying neurofunctional abnormalities of autism, the authors performed single photon emission computed...
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No Association Study of SLC6A4 Polymorphisms with Korean Autism Spectrum Disorder

Yoo HJ, Cho IH, Park M, Yang SY, Kim SA

  • KMID: 2299975
  • Korean J Biol Psychiatry.
  • 2009 May;16(2):121-126.
OBJECTIVES : The serotonin transporter gene(SLC6A4) is one of the most widely studied candidate genes in autism spectrum disorder(ASD), but there have been conflicting results from studies into the association...
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Well Baby Clinic: Developmental Guidance according to the Parent's Chief Complaints

Kim SW, Kim YK, Chung HJ

Despite the relatively high prevalence (5~10%) of developmental disability, the early identification for such problems remains difficult. Doctors who care children with developmental delay tried to find out these disorders...
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Effects of Massage and Attachment Promotion Program on Social Maturity, Child Autism and Attachment of Children with Autism and Their Mothers

Lee HK

  • KMID: 2291940
  • J Korean Acad Child Health Nurs.
  • 2008 Jan;14(1):14-21.
PURPOSE: The aims of this study were to evaluate effects of massage therapy and the attachment promotion program with autistic children. METHOD: A quasi-experimental design was conducted with a convenience sample...
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Development of an Interaction Behaviors Checklist for Early Detection of Autistic Children

Im SB

  • KMID: 1754014
  • J Korean Acad Nurs.
  • 2005 Feb;35(1):5-15.
PURPOSE: This study was conducted to develop a behavioral checklist to predict an autistic disorder and to identify the earliest detecting time. METHOD: One hundred and fifty eight...
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