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1 Gold compound auranofin inhibits I kappaB kinase (IKK) by modifying Cys-179 of IKK beta subunit

Jeon KI, Byun MS, Jue DM

KMID: 1097252
Exp Mol Med.
2003 Apr;35(2):61-66.

Antirheumatic gold compounds have been shown to inhibit NF-kB activation by blocking IkB kinase (IKK) activity. To examine the possible inhibitory mechanism of gold compounds, we expressed wild type and...

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