- Auranofin Suppresses Plasminogen Activator Inhibitor-2 Expression through Annexin A5 Induction in Human Prostate Cancer Cells
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Shin DW, Kwon YJ, Ye DJ, Baek HS, Lee JE, Chun YJ
- KMID: 2375038
- Biomol Ther.
- 2017 Mar;25(2):177-185.
- doi: 10.4062/biomolther.2016.223
Auranofin has been developed as antirheumatic drugs, which is currently under clinical development for the treatment of chronic lymphocytic leukemia. Previous report showed that auranofin induced apoptosis by enhancement of... -
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- Gold compound auranofin inhibits I kappaB kinase (IKK) by modifying Cys-179 of IKK beta subunit
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Jeon KI, Byun MS, Jue DM
- KMID: 1097252
- Exp Mol Med.
- 2003 Apr;35(2):61-66.
Antirheumatic gold compounds have been shown to inhibit NF-kB activation by blocking IkB kinase (IKK) activity. To examine the possible inhibitory mechanism of gold compounds, we expressed wild type and... -
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- The Effect of Auranofin on Thrombomodulin Expression in Acute Promyelocytic Leukemia Cell
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Lee IH, Jin JY, Kim MS, Kim IS
- KMID: 1610806
- Korean J Hematol.
- 2005 Sep;40(3):135-141.
- doi: 10.5045/kjh.2005.40.3.135
BACKGROUND: Acute promyelocytic leukemia (APL) is distinguished from other forms of leukemia by its association with bleeding diatheses. All-trans retinoic acid (ATRA) and arsenic trioxide (As2O3), which have been effectively... -
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