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DNA methylation in human papillomavirus-infected cervical cells is elevated in high-grade squamous intraepithelial lesions and cancer

Kim MK, Lee IH, Lee KH, Lee YK, So KA, Hong SR, Hwang CS, Kee MK, Rhee JE, Kang C, Hur SY, Park JS, Kim TJ

OBJECTIVE: DNA methylation has been shown to be a potential biomarker for early cancer detection. The aim of this study was to evaluate DNA methylation profiles according to liquid-based Pap...
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High-risk human papillomavirus genotype distribution and attribution to cervical cancer and precancerous lesions in a rural Chinese population

Zhao XL, Hu SY, Zhang Q, Dong L, Feng RM, Han R, Zhao FH

OBJECTIVE: To explore the genotype distribution of high-risk human papillomavirus (HR-HPV) and its attribution to different grades of cervical lesions in rural China, which will contribute to type-specific HPV screening...
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