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Astaxanthin Inhibits Helicobacter pylori-induced Inflammatory and Oncogenic Responses in Gastric Mucosal Tissues of Mice

Han H, Lim JW, Kim H

Helicobacter pylori is recognized as a risk factor for gastric carcinogenesis. The chronic exposure of gastric epithelium to H. pylori induces a prolonged inflammatory state that may progress to gastric...
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Combination Effect of Titrated Extract of Centella asiatica and Astaxanthin in a Mouse Model of Phthalic Anhydride-Induced Atopic Dermatitis

Park JH, Yeo IJ, Jang JS, Kim KC, Park MH, Lee HP, Han SB, Hong JT

PURPOSE: In our previous study, we demonstrated that both titrated extract of Centella asiatica (TECA) and astaxanthin (AST) have anti-inflammatory effects in a 5% phthalic anhydride (PA) mouse model of...
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Astaxanthin Prevents Decreases in Superoxide Dismutase 2 Level and Superoxide Dismutase Activity in Helicobacter pylori-infected Gastric Epithelial Cells

Kim SH, Lim JW, Kim H

BACKGROUND: Helicobacter pylori increases production of reactive oxygen species (ROS), which activates inflammatory and carcinogenesis-related signaling pathways in gastric epithelial cells. Therefore, reducing ROS, by upregulating antioxidant enzyme, such as...
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Astaxanthin and β-carotene in Helicobacter pylori-induced Gastric Inflammation: A Mini-review on Action Mechanisms

Kang H, Kim H

Helicobacter pylori is a dominant bacterium living in the human gastric tissues. In H. pylori-infected tissues, the infiltrated inflammatory cells produce reactive oxygen species (ROS), leading to gastric inflammation with...
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Dietary supplementation with astaxanthin may ameliorate sperm parameters and DNA integrity in streptozotocin-induced diabetic rats

Bahmanzadeh M, Vahidinia , Mehdinejadiani S, Shokri S, Alizadeh Z

OBJECTIVE: Diabetes mellitus (DM) is known to cause many systemic complications as well as male infertility. Astaxanthin (ASTX) is a powerful antioxidant that is involved in a variety of biologically...
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Astaxanthin Inhibits Proliferation of Human Gastric Cancer Cell Lines by Interrupting Cell Cycle Progression

Kim JH, Park JJ, Lee BJ, Joo MK, Chun HJ, Lee SW, Bak YT

BACKGROUND/AIMS: Astaxanthin is a carotenoid pigment that has antioxidant, antitumoral, and anti-inflammatory properties. In this in vitro study, we investigated the mechanism of anticancer effects of astaxanthin in gastric carcinoma...
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Nephroprotective effect of astaxanthin against trivalent inorganic arsenic-induced renal injury in wistar rats

Wang X, Zhao H, Shao Y, Wang P, Wei Y, Zhang W, Jiang J, Chen Y, Zhang Z

  • KMID: 2313710
  • Nutr Res Pract.
  • 2014 Feb;8(1):46-53.
Inorganic arsenic (iAs) is a toxic metalloid found ubiquitously in the environment. In humans, exposure to iAs can result in toxicity and cause toxicological manifestations. Arsenic trioxide (As2O3) has been...
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Anticancer Effects of Astaxanthin and alpha-tocopherol in Esophageal Cancer Cell Lines

Lim SA, Lee JY, Jung WH, Lim EH, Joo MK, Lee BJ, Park JJ, Kim JS, Bak YT, Jung SW, Lee SW

BACKGROUND/AIMS: Astaxanthin (AX) has been attributed with potential for protecting the organism against different types of cancer due to its anti-oxidant activity. Also several in vivo and in vitro studies...
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Antioxidant Effects of Haematococcus Extracts for Ischemia-Reperfusion Injury on Liver of Mice

Yun IJ, Ahn MS, Kim DC, You BI, Lee GK, Ha J, Kim SJ

  • KMID: 2244266
  • Korean J Hepatobiliary Pancreat Surg.
  • 2004 Sep;8(3):152-159.
PURPOSE: An IRI (Ischemia-reperfusion injury) of the liver is one of the main problems in major liver surgery, liver transplantation and liver trauma, which can lead to liver failure. The...
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