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Dehydroepiandrosterone-dependent induction of peroxisomal proliferation can be reduced by aspartyl esterification without attenuation of inhibitory bone loss in ovariectomy animal model

Kwak CS, Kang CM, Kang HS, Song KY, Lee MS, Seong SC, Park SC

The purpose of this study was to determine whether esterification of dehydroepiandrosterone with aspartate (DHEA-aspartate) could reduce peroxisomal proliferation induced by DHEA itself, without loss of antiosteoporotic activity. Female Sprague-Dawley...
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Asp 280 residue is important in the activity of the Escherichia coli leader peptidase

Sung MS, Park KS

  • KMID: 1029933
  • Exp Mol Med.
  • 1999 Jun;31(2):64-69.
Leader peptidase is a novel serine protease in Escherichia coli, which catalyzes the cleavage of amino-terminal signal sequences from exported proteins. It is an integral membrane protein containing two transmembrane segments with...
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