- Quantitative Evaluation of Liver Function with Hepatic Receptor Scintigraphy using Tc-99m Galactosylated Serum Albumin ( GSA )
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Lee J
- KMID: 2078707
- Korean J Nucl Med.
- 1998 Aug;32(4):305-313.
The reduction in the amount of asialoglycoprotein (ASGP) receptor, which resides exclusively on the plasma membrane of functioning mammalian hepatocytes, as a consequence of hepato-cellular damage has been demonstrated in... -
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- Hepatic Asialoglycoprotein Receptor Scintigraphy Using 99mTc - Galactosylated Serum Albumin ( GSA ): Biodistribution Study in Mice with Thioacetamide - induced Hepatic Injury
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Hyun DW, Lee JT, Chun KA, Lee SW, Kim SK, Kang DY, Kwon YO, Sohn YK, Lee KB, Chung JM
- KMID: 2143304
- Korean J Hepatol.
- 1998 Jun;4(2):151-161.
BACKGROUND/AIMS: Tc-DTPA-galactosylated serum albumin (GSA) is a new liver imaging agent that specifically binds to asialoglycoprotein receptor, which resides exclusively on the plasma membrane of mammalian hepatocytes. To evaluate the usefulness of... -
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- 99mTc-DTPA Galactosyl Human Serum Albumin Scintigraphy in Mushiroom Poisoning Patient: Comparison with Liver Ultrasonography
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Jeong SY, Lee J, Bae JH, Chun KA, Ahn BC, Kang YM, Jeong JM, Lee KB
- KMID: 1516884
- Korean J Nucl Med.
- 2003 Aug;37(4):254-259.
99mTc-galactosyl human serum albumin (Tc-GSA) is a radiopharmaceutical that binds to asialoglycoprotein receptors, which are specifically present in the hepatocyte membrane. Because these receptors are decreased in hepatic parenchymal damage,... -
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- Biodistribution of (99m) Tc-Lactosylated Serum Albumin in Mice with Diethylnitrosamine or Thiacetamide Induced Liver Injury
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Whang JS, Ahn BC, Sung YO, Seo JH, Bae JH, Jeong SY, Yoo JS, Jeong JM, Lee J, Lee KB
- KMID: 2078820
- Korean J Nucl Med.
- 2005 Jun;39(3):200-208.
PURPOSE: Tc-99m labeled diethylenetriaminepentaacetic acid (DTPA) -coupled galactosylated human serum albumin (GSA) is a currently used imaging agent for asialoglycoprotein receptor (ASGPR) of the liver, but, it has several shortcomings.... -
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- Evaluation of Liver Function Using 99mTc-Lactosylated Serum Albumin Liver Scintigraphy in Rat with Acute Hepatic Injury Induced by Dimethylnitrosamine
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Jeong SY, Lee J, Seo M, Yoo JA, Bae JH, Ahn BC, Hwang JS, Jeong JM, Ha JH, Lee KB
- KMID: 1516877
- Korean J Nucl Med.
- 2003 Dec;37(6):418-427.
OBJECTS: 99mTc-lactosylated human serum albumin (LSA) is a newly synthesized radiopharmaceutical that binds to asialoglycoprotein receptors, which are specifically presented on the hepatocyte membrane. Hepatic uptake and blood clearance of... -
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