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Innovation in Asia Pacific Allergy

Chang YS

No abstract available.
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Interleukin-10 is increased in successful drug desensitization regardless of the hypersensitivity reaction type

Gelincik A, Demir S, Şen F, Bozbey UH, Olgaç M, Ünal D, Çolakoğlu B, Aktaş EC, Deniz G, Büyüköztürk S

BACKGROUND: Little is known about the mechanism of desensitization in hypersensitivity drug reactions. OBJECTIVE: The aim of this study was to evaluate the effects of drug desensitization on some cytokine levels...
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School-aged asthma children with high fractional exhaled nitric oxide levels and lung dysfunction are at high risk of prolonged lung dysfunction

Saito M, Kikuchi Y, Lefor AK

BACKGROUND: Long-term management of bronchial asthma based on the fractional exhaled nitric oxide (FeNO) value alone is not conclusive yet. Therefore, we combined FeNO testing and spirometry, a commonly used...
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Omalizumab and unmet needs in severe asthma and allergic comorbidities in Japanese children

Nishima S, Kozawa M, Milligan K, Papadopoulos NG

Childhood asthma is one condition within a family of allergic diseases, which includes allergic rhinitis, atopic dermatitis, and food allergy, among others. Omalizumab is an anti-IgE antibody therapy that was...
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Minimal clinically important difference for the rhinoconjunctivitis quality of life questionnaire in allergic rhinitis in Thai population

Tantilipikorn P, Saisombat , Phonpornpaiboon P, Pinkaew B, Lermankul , Bunnag C

BACKGROUND: Clinical measurement of the severity of allergic rhinitis (AR) can be assessed by symptoms score and patient quality of life (QoL). The magnitude of change in both symptoms and...
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Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study

Mitsui-Iwama M, Yamamoto-Hanada K, Fukutomi Y, Hirota R, Muto G, Nakamura T, Yoshikawa , Nakamura H, Mikami M, Morioka I, Ohya Y

BACKGROUND: Previous studies have reported that exposure to paraben (Pb) and triclosan (TCS) is associated with allergies. However, Pb and TCS exposure in the Japanese population is not fully understood. OBJECTIVES:...
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Human ex vivo and in vitro disease models to study food allergy

Hung L, Obernolte , Sewald K, Eiwegger T

Food allergy is a growing global public health concern. As treatment strategies are currently limited to allergen avoidance and emergency interventions, there is an increasing demand for appropriate models of...
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A case of anhidrotic ectodermal dysplasia presenting with pyrexia, atopic eczema, and food allergy

Suzuki T, Tajima H, Migita M, Pawankar R, Yanagihara T, Fujita A, Shima Y, Yanai E, Katsube Y

Anhidrotic ectodermal dysplasia (AED) is a rare hereditary disorder with a triad of sparse hair, dental hypoplasia, and anhidrosis. Here we report a case of AED with food allergy and...
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Allergy to carminic acid: in vitro evidence of involvement of protein-binding hapten

Osumi M, Yamaguchi , Sugimoto N, Suzukawa M, Arai H, Akiyama H, Nagase H, Ohta K

We previously described a rare case of anaphylaxis presumably induced by carminic acid in cochineal dye used as a food additive. In this study, highly pure carminic acid was added...
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Efficacy and safety of oral immunotherapy for peanut allergy: a pilot study in Singaporean children

Zhong Y, Chew JM, Tan MM, Soh JY

BACKGROUND: Peanut allergy is an increasing problem in Singapore and strict avoidance is difficult as peanut is ubiquitous in Asian cuisine. OBJECTIVE: We aimed to assess the efficacy and safety of...
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