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Recurrent intradialytic heparin induced anaphylaxis: workup and management

Santosa A, Tan SH, Cheng YK

Heparin has been widely used for intradialytic anticoagulation since the 1940s. Heparin induced anaphylaxis can be life threatening, mandating early recognition and intervention. However, due to its relative rarity many...
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A case of levocetirizine-induced fixed drug eruption and cross-reaction with piperazine derivatives

Kim MY, Jo EJ, Chang YS, Cho SH, Min KU, Kim SH

Fixed drug eruption is an uncommon adverse drug reaction caused by delayed cell-mediated hypersensitivity. Levocetirizine is an active (R)-enatiomer of cetirizine and there have been a few reports of fixed...
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Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity

Song WJ, Chang YS

Immediate-type drug hypersensitivity is an increasingly significant clinical issue; however, the diagnosis is frequently hindered due to lack of safe and precise diagnostic tests. Flow cytometry-assisted basophil activation test is...
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Nuts 'n' guts: transport of food allergens across the intestinal epithelium

Price D, Ackland L, Suphioglu

The increase in the incidence of food allergy is a growing problem for the western world. This review will focus on the findings from several macromolecular epithelial transport experiments and...
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Adverse events of intravenous immunoglobulin infusions: a ten-year retrospective study

Palabrica , Kwong SL, Padua FR

BACKGROUND: Intravenous immunoglobulin (IVIG) is a biological product with adverse effects that appears to vary considerably among different IVIG preparations. OBJECTIVES: To describe the adverse events of patients given intravenous immunoglobulin...
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Immediate and nonimmediate reactions induced by contrast media: incidence, severity and risk factors

Bedolla-Barajas M, Hernández-Colín DD, Morales-Romero J, Serrano-Salinas C

BACKGROUND: The pattern of the contrast media-induced adverse reactions has not been investigated extensively in Mexico. OBJECTIVE: To estimate the incidence and the degree of severity of the adverse reactions to...
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CYP1A2 polymorphism and theophylline clearance in Korean non-smoking asthmatics

Yim EY, Kang HR, Jung JW, Sohn SW, Cho SH

BACKGROUND: Theophylline is mainly metabolized by cytochrome P450 (CYP) 1A2 and CYP2E1 which show inter-individual variations. However, the underlying mechanism remains unknown in humans. We investigated the relationship between differences...
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Measuring and imaging small airways dysfunction in asthma

Thien F

Asthma is a chronic inflammatory disorder of the airways causing typical symptoms, and the diagnosis is supported by evidence of airflow obstruction which is variable, reversible or inducible. However, standard...
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Stevens-Johnson syndrome / toxic epidermal necrolysis: an Asia-Pacific perspective

Thong BY

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions (SCAR) to drugs which are associated with significant morbidity and mortality. High risk drugs in Asia are...
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What Taiwan contributes to the world of allergy and clinical immunology?

Wang JY

In commemorate the 9th Asia Pacific Congress of Allergy, Asthma, and Clinical Immunology (APCAACI) in Taipei, Taiwan in November this year, some of the seminar works and contributions by the...
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Allergic diseases in the Asia Pacific: path into the future

Wong GW

No abstract available.
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