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Paraoxonase Gene Polymorphism in South-western Korean Population

Shin BS

Paraoxonase (PON) has anti-atherogenic activity. Considering the important role of polymorphism in the genetic susceptibility to cardiovascular disease and the variability of its allele frequencies in different ethnic groups, the...
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Association of Paraoxonase 1 (PON1) polymorphisms with osteoporotic fracture risk in postmenopausal Korean women

Kim BJ, Kim SY, Cho YS, Kim BJ, Han BG, Park EK, Lee SH, Kim HY, Kim GS, Lee JY, Koh JM

There is increasing evidence of a biochemical link between lipid oxidation and bone metabolism. Paraoxonase 1 (PON1) prevents the oxidation of low-density lipoprotein (LDL) and metabolizes biologically active phospholipids in...
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Effects of Oxidative DNA Damage Induced by Polycyclic Aromatic Hydrocarbons and Genetic Polymorphism of the Paraoxonase-1 (PON1) Gene on Lung Cancer

Lee CH, Lee KY, Choe KH, Hong YC, Kim YD, Kang JW, Kim H

  • KMID: 1083325
  • J Prev Med Public Health.
  • 2005 Aug;38(3):345-350.
OBJECTIVE: Polycyclic aromatic hydrocarbons (PAHs), which are risk factors for lung cancer, have been reported to induce oxidative DNA damage. The paraoxonase (PON) plays a significant role in the detoxification...
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