- New conceptual approaches toward dentin regeneration using the drug repositioning strategy with Wnt signaling pathways
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Lee ES, Kim TY, Aryal YP, Kim K, Byun S, Song D, Shin Y, Lee D, Lee J, Jung G, Chi S, Choi Y, Lee Y, An CH, Kim JY
- KMID: 2517069
- Int J Oral Biol.
- 2021 Jun;46(2):67-73.
- doi: 10.11620/IJOB.2021.46.2.67
This study summarizes the recent cutting-edge approaches for dentin regeneration that still do not offer adequate solutions. Tertiary dentin is formed when odontoblasts are directly affected by various stimuli. Recent... -
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- Implications of specific gene expression patterns in enamel knot in tooth development
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Kim TY, Neupane S, Aryal YP, Lee ES, Kim JY, Suh JY, Lee Y, Sohn WJ, An SY, Ha JH, An CH, Kim JY
- KMID: 2507067
- Int J Oral Biol.
- 2020 Mar;45(1):25-31.
- doi: 10.11620/IJOB.2020.45.1.25
Enamel knot (EK)—a signaling center—refers to a transient morphological structure comprising epithelial tissue. EK is believed to regulate tooth development in early organogenesis without its own cellular alterations, including proliferation... -
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- Alteration of cellular events in tooth development by chemical chaperon, Tauroursodeoxycholic acid treatment
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Lee ES, Aryal YP, Kim TY, Pokharel E, Kim H, Sung S, Sohn WJ, Lee Y, An CH, Kim JY
- KMID: 2510199
- Int J Oral Biol.
- 2020 Dec;45(4):190-196.
- doi: 10.11620/IJOB.2020.45.4.190
Several factors, including genetic and environmental insults, impede protein folding and secretion in the endoplasmic reticulum (ER). Accumulation of unfolded or mis-folded protein in the ER manifests as ER stress.... -
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