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Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis

Jue DM, Jeon KI, Jeong JY

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by persistent joint swelling and progressive destruction of cartilage and bone. Current RA treatments are largely empirical in origin and their...
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NRAMP1 gene polymorphisms in patients with rheumatoid arthritis in Koreans

Yang YS, Kim SJ, Kim JW, Koh EM

Natural resistance-associated macrophage protein 1 (Nramp1) is a genetic locus associated with innate resistance or susceptibility of murine hosts to infection with intracellular pathogens such as Salmonella, Leishmania and Mycobacterium....
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Urinary N-acetyl-beta-D-glucosaminidase in rheumatoid arthritis

Iqbal MP, Ali AA, Waqar MA, Mehboobali N

  • KMID: 1109300
  • Exp Mol Med.
  • 1998 Sep;30(3):165-169.
Excretion of urinary N-acetyl beta-D-glucosaminidase (NAG) and its isoenzyme patterns were studied in two groups of patients with rheumatoid arthritis (RA) and in normal control subjects. Urine samples were collected from 30 seropositive...
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In Vitro Study of Nonspecific Cellular Immunity in Rheumatoid Arthritis

Hong KP, Choi IH, Kim GS, Lee BK, Youn JK, Park BM

Nonspecific immune parameters such as natural killer(NK) activity, antibody-dependent cellular cytotoxicity(ADCC), production of leukocyte migration inhibitory factor(LlF) and levels of immune complex(IC) were assessed in 47 patients with rheumatoid arthritis...
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Regulatory T-cell vaccination independent of auto-antigen

Pascual DW, Yang X, Holderness K, Jun S, Maddaloni , Kochetkova I

To date, efforts to treat autoimmune diseases have primarily focused on the disease symptoms rather than on the cause of the disease. In large part, this is attributed to not...
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Clinical Significance of Dense Fine Speckled Pattern in Anti-nuclear Antibody Test using Indirect Immunofluorescence Method

Kang SY, Lee WI

BACKGROUND: Dense fine speckled (DFS) pattern in antinuclear antibody (ANA) test using indirect immunofluorescence method became to be known recently and it is detected in patients with various chronic inflammatory...
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