- Role of Helix 8 in Dopamine Receptor Signaling
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Yang HS, Sun N, Zhao X, Kim HR, Park HJ, Kim KM, Chung KY
- KMID: 2462878
- Biomol Ther.
- 2019 Nov;27(6):514-521.
- doi: 10.4062/biomolther.2019.026
G protein-coupled receptors (GPCRs) are membrane receptors whose agonist-induced dynamic conformational changes trigger heterotrimeric G protein activation, followed by GRK-mediated phosphorylation and arrestin-mediated desensitization. Cytosolic regions of GPCRs have been... -
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