- Massive Identification of Cancer-Specific Nucleic Acid Ligands
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Lee YJ, Lee SW
- KMID: 1572640
- Genomics Inform.
- 2005 Jun;3(2):77-80.
Targeting of complex system such as human cells rather than biochemically pure molecules will be a useful approach to massively identify ligands specific for the markers associated with human disease... -
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- Cotinine-conjugated aptamer/anti-cotinine antibody complexes as a novel affinity unit for use in biological assays
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Park S, Hwang D, Chung J
- KMID: 1389735
- Exp Mol Med.
- 2012 Sep;44(9):554-561.
Aptamers are synthetic, relatively short (e.g., 20-80 bases) RNA or ssDNA oligonucleotides that can bind targets with high affinity and specificity, similar to antibodies, because they can fold into unique,... -
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- Isolation of MLL1 Inhibitory RNA Aptamers
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Ul-Haq A, Jin ML, Jeong KW, Kim HM, Chun KH
- KMID: 2442012
- Biomol Ther.
- 2019 Feb;27(2):201-209.
- doi: 10.4062/biomolther.2018.157
Mixed lineage leukemia proteins (MLL) are the key histone lysine methyltransferases that regulate expression of diverse genes. Aberrant activation of MLL promotes leukemia as well as solid tumors in humans,... -
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