- The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells
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Han JY, Chung YJ, Park SW, Kim JS, Rhyu MG, Kim HK, Lee KS
- KMID: 759083
- Korean J Intern Med.
- 1999 Jan;14(1):42-52.
OBJECTIVES: Given the roles of bcl-2, bax and p53 in apoptosis, we investigated the effect of their expression on the response to cisplatin in order to understand the... -
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- Enhanced induction of Bax gene expression in H460 and H1299 cells with the combined treatment of cisplatin and adenovirus mediated wt-p53 gene transfer
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Choi JH, Ahn KS, Kim JG, Hong YS
- KMID: 927130
- Exp Mol Med.
- 2000 Mar;32(1):23-28.
Cytotoxic effect of either cisplatin or p53 gene transfection of lung cancer cells may be different depending on the p53 status of cells. We investigated cytotoxic effects on the combined... -
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- Downregulation of cellular prion protein inhibited the proliferation and invasion and induced apoptosis of Marek's disease virus-transformed avian T cells
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Wan X, Yang R, Liu G, Zhu M, Zhang T, Liu L, Wu R
- KMID: 2413166
- J Vet Sci.
- 2016 Jun;17(2):171-178.
- doi: 10.4142/jvs.2016.17.2.171
Cellular prion protein (PrP(C)) is ubiquitously expressed in the cytomembrane of a considerable number of eukaryotic cells. Although several studies have investigated the functions of PrP(C) in cell proliferation, cell... -
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- Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin)
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Song SU, Boyce FM
- KMID: 755117
- Exp Mol Med.
- 2001 Mar;33(1):46-53.
The insect baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) has been evaluated as a vector for gene delivery to human tumor cells. A human osteogenic sarcoma cell line, Saos-2,... -
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- Molecular Mechanisms of Hepatitis B Virus-associated Hepatocellular Carcinoma
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Park NH, Chung YH
- KMID: 760734
- Korean J Hepatol.
- 2007 Sep;13(3):320-340.
- doi: 10.3350/kjhep.2007.13.3.320
Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. The hepatitis B virus (HBV) replicates non-cytopathically in hepatocytes, and most of the liver injury associated... -
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- Iron-induced cytotoxicity in cultured rat retinal neurons
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Sohn J, Yoon YH
- KMID: 1043979
- Korean J Ophthalmol.
- 1998 Dec;12(2):77-84.
- doi: 10.3341/kjo.1998.12.2.77
Oxidative stress has been proposed as a major injury mechanism in the central nervous system including the retina. In this study, as an initial attempt to study the mechanism of... -
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