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Kinetin inhibits apoptosis of aging spleen cells induced by D-galactose in rats

Li M, Ouyang W, Wu X, Zheng Y, Wei Y, An L

Kinetin (Kn) is a cytokinin growth factor that exerts several anti-aging and antioxidant effects on cells and organs. To investigate the mechanism underlying apoptotic events in aging cells induced by...
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D4-GDI is cleaved by caspase-3 during daunorubicin-induced apoptosis in HL-60 cells

Kwon KB, Park EK, Ryu DG, Park BH

  • KMID: 1093595
  • Exp Mol Med.
  • 2002 Mar;34(1):32-37.
Daunorubicin, an anti-cancer drug, is known to induce apoptosis in HL-60 cells in a dose-dependent manner through the activation of caspase-3 (CPP32). Caspase-3 selective inhibitor, Ac-DEVD-CHO, prevented both the activation...
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Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2

Kim BE, Lee JH, Kim HS, Kwon OJ, Jeong SW, Kim IK

  • KMID: 1123765
  • Exp Mol Med.
  • 2004 Oct;36(5):444-453.
delta12-Prostaglandin (PG) J2 is known to elicit an anti-neoplastic effects via apoptosis induction. Previous study showed delta12-PGJ2-induced apoptosis utilized caspase cascade through cytochrome c-dependent pathways in HeLa cells. In this...
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Anti-apoptotic role of phospholipase D isozymes in the glutamate-induced cell death

Kim KO, Lee KH, Kim YH, Park SK, Han JS

  • KMID: 1088656
  • Exp Mol Med.
  • 2003 Feb;35(1):38-45.
Abstract Phospholipase D (PLD) plays an important role as an effector in a variety of physiological processes that reveal it to be a member of the signal transducing phospholipases. Recently,...
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