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Apolipoproteins as Differentiating and Predictive Markers for Assessing Clinical Outcomes in Patients with Small Cell Lung Cancer

Shi J, Yang H, Duan X, Li L, Sun L, Li Q, Zhang J

PURPOSE: The present study aimed to investigate the value of apolipoproteins, including ApoA-1, ApoC-III, and ApoE, in patients with small cell lung cancer (SCLC) as potential biomarkers for diagnosis, prognosis,...
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Apolipoprotein E Genotype in Korean Schizophrenic Patients

Lee MK, Park AJ, Nam BY, Min KJ, Kee BS, Park DB

The apolipoprotein E (APOE) epsilon4 allele is a known risk factor for the development of Alzheimer's disease, however, an association of the APOE genotype with schizophrenia is controversial. We investigated...
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Important Link between Dementia Subtype and Apolipoprotein E: a Meta-analysis

Bang OY, Kwak YT, Joo IS, Huh K

To evaluate the differential diagnostic role of apolipoprotein E (apoE) genotype in dementia, we carried out a meta- analysis of 78 case-control series, including our own new data. The dementia...
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Discrepancy in Genotyping of Apolipoprotein E between Allele-Specific PCR and Fluorescence Resonance Energy Transfer or Sequencing

Park CH, Lee ST, Ki CS, Kim JW

The human apolipoprotein E (APOE) gene contains several single-nucleotide polymorphisms (SNPs) that are distributed across the gene. The genotype of the APOE gene has important implications as a risk factor...
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Apolipoprotein E genotypes of normal and hyperlipidemic subjects

Kim YS, Paeng JR, Woo JT, Kim SW, Yang IM, Kim JW, Kim KW, Choi YK

Apolipoprotein E (apo E) plays a role in the regulation of the lipid metabolism of humans. Apo E, 229 amino acid polypeptide, is classified into three major isoform (E2, E3,...
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The enhanced expression of IL-17-secreting T cells during the early progression of atherosclerosis in ApoE-deficient mice fed on a western-type diet

Jeon US, Choi JP, Kim YS, Ryu SH, Kim YK

Atherosclerosis is a chronic progressive inflammatory disorder and the leading cause of cardiovascular mortality. Here we assessed the dynamic changes of T-cell-derived cytokines, such as inteferon (IFN)-gamma, interleukin (IL)-17 and...
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Identification of PSEN1 and APP Gene Mutations in Korean Patients with Early-Onset Alzheimer's Disease

Park HK, Na DL, Lee JH, Kim JW, Ki CS

Although mutations in three genes, amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2), have been identified as genetic causes of earlyonset Alzheimer s disease (EOAD), there has...
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Relation of Apolipoprotein E Polymorphism to Clinically Diagnosed Fatty Liver Disease

Lee DM, Lee SO, Mun BS, Ahn HS, Park HY, Lee HS, Kim DG

  • KMID: 863110
  • Korean J Hepatol.
  • 2002 Dec;8(4):355-362.
BACKGROUND/AIMS: Apolipoprotein E (Apo E) is important in plasma lipid metabolism and is a component of several plasma lipoprotein-lipid particles. Three major Apo E isoforms are encoded by three...
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Apolipoprotein E Gene Polymorphism and Serum Lipids in Patients with Superficial Fungal Disease

Tursen U, Kaya TI, Eskandari , Bocekli E, Muslu N, Camdeviren H, Ikizoglu G, Atik U

Superficial mycosis, including dermatophytic infections, tinea versicolor, and cutaneous candidiasis is mostly limited to the outer layers of the skin, nails, and mucous membranes. In this study, Apolipoprotein E (ApoE)...
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Apolipoprotein E Polymorphism and Cognitive Function Change of the Elderly in a Rural Area, Korea

Kim SK, Hwang TY, Lee KS, Kang PS, Cho HS, Bae YK

OBJECTIVES: The aim of this study is to examine the cognitive function change related to aging, the incidence of cognitive impairment, and the association between apolipoprotein E polymorphism and cognitive...
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APOE Polymorphism Is Associated with C-reactive Protein Levels but Not with White Blood Cell Count: Dong-gu Study and Namwon Study

Yun YW, Kweon SS, Choi JS, Rhee JA, Lee YH, Nam HS, Jeong SK, Park KS, Ryu SY, Choi SW, Kim HN, Cauley JA, Shin MH

We evaluated the association of the APOE polymorphism with serum C-reactive protein levels and white blood cell count in two large population-based studies in Korean. The datasets included the Dong-gu...
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The Effect of Apolipoprotein E Polymorphism on Lipid Levels in Korean Adults

Shin MH, Kim HN, Cui LH, Kweon SS, Park KS, Heo H, Nam HS, Jeong SK, Chung EK, Choi JS

The aim of this study was to determine the effects of polymorphisms in the apolipoprotein E gene (APOE) on lipid levels in Korean adults and to investigate the interactions between...
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ApoE Polymorphism May Determine Low-Density Lipoprotein Cholesterol Level in Association with Obesity and Metabolic Syndrome in Postmenopausal Korean Women

Lee DJ, Kim KM, Kim BT, Kim KN, Joo NS

PURPOSE: We investigated how serum low-density lipoprotein (LDL) level is related to various isoforms of apolipoprotein (ApoE) polymorphism in association with obesity and metabolic syndrome. MATERIALS AND METHODS: We gathered total...
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Inflammatory Marker Expression and Its Implication in Korean Ischemic Stroke Patients

Park SY, Kim MH, Kang SY, Suh JT, Lee WI

BACKGROUND: Ischemic stroke is a complex condition influenced by many factors. Previous studies have demonstrated that inflammatory markers might play a role in such vascular diseases. Therefore the purpose...
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Association between apolipoprotein E genotype, chronic liver disease, and hepatitis B virus

Ahn SJ, Kim DK, Kim SS, Bae CB, Cho HJ, Kim HG, Kim YJ, Lee JH, Lee HJ, Lee MY, Kim KB, Cho JH, Cho SW, Cheong JY

BACKGROUND/AIMS: Apolipoprotein E (ApoE) plays an important role in regulating lipid and lipoprotein metabolism, and ApoE genotypes are known to affect plasma lipoprotein concentrations. We investigated whether ApoE genotype determines...
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