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The Expression of Aphidicolin Induced Fragile Sites in Human Peripheral Blood Lymphocytes

Park KR, Zheng GD

  • KMID: 2224587
  • Korean J Anat.
  • 1999 Apr;32(2):261-268.
An aphidicolin is a chemical agent which selectively inhibits DNA polymerase alpha in S phase of cell cycle. The purpose of this study is toinvestigate of chromosomal abnormalities including fragile...
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Fragile sites induced by aphidicolin in lymphocytes, HaCat cells and MRC-5 cells

Park KR, Goo DE, Lee JH, Kim WS, Lee YH, Kwon OY, Chang SI

  • KMID: 1937889
  • Korean J Anat.
  • 1998 Oct;31(5):785-790.
To investigate fragile sites induced by aphidicolin which is a specific inhibitor of eukaryotic DNA polymerase a which is primarily associated with chromosomal DNA replication in human lymphocytes, HaCat cells...
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RNA-sequencing Profiles of Cell Cycle–Related Genes Upregulated during the G2-Phase in Giardia lamblia

Kim J, Shin MY, Park SJ

To identify the component(s) involved in cell cycle control in the protozoan Giardia lamblia, cells arrested at the G1/S- or G2-phase by treatment with nocodazole and aphidicolin were prepared from...
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Impairment of Neurite Formation in Familial ALS-associated Cu, Zn-Superoxide Dismutase Mutant Cells

Park KS, Kim HJ, Kim MH, Lee KW

  • KMID: 2137973
  • J Korean Neurol Assoc.
  • 2002 Nov;20(6):694-698.
BACKGROUND: Mutations in the human Cu, Zn-superoxide dismutase (SOD1) gene have been identified in some cases of familial amyotrophic lateral sclerosis (ALS). Neuronal cells with mutant SOD1 gene promoted cell...
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Effect of Familial Amyotrophic Lateral Sclerosis-associated Cu, Zn-superox-ide Dismutase Mutation on Neural Differentiation in Motor Neuronal Cells

Park KS, Kim HJ, Kim NH, Kim MH, Park SH, Park WY, Kim YS, Lee BL, Cha CI, Chae YS, Lee KW

  • KMID: 2342972
  • J Korean Neurol Assoc.
  • 2002 May;20(3):273-278.
BACKGROUND: Mutations in the human Cu, Zn-superoxide dismutase(SOD1) gene have been identified in some cases of familial amyotrophic lateral sclerosis(ALS). The aim of this study is to delineate the effect...
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