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An aphidicolin is a chemical agent which selectively inhibits DNA polymerase alpha in S phase of cell cycle. The purpose of this study is toinvestigate of chromosomal abnormalities including fragile...
Park KR, Goo DE, Lee JH, Kim WS, Lee YH, Kwon OY, Chang SI
KMID: 1937889
Korean J Anat.
1998 Oct;31(5):785-790.
To investigate fragile sites induced by aphidicolin which is a specific inhibitor of eukaryotic DNA polymerase a which is primarily associated with chromosomal DNA replication in human lymphocytes, HaCat cells...
To identify the component(s) involved in cell cycle control in the protozoan Giardia lamblia, cells arrested at the G1/S- or G2-phase by treatment with nocodazole and aphidicolin were prepared from...
BACKGROUND: Mutations in the human Cu, Zn-superoxide dismutase (SOD1) gene have been identified in some cases of familial amyotrophic lateral sclerosis (ALS). Neuronal cells with mutant SOD1 gene promoted cell...
Park KS, Kim HJ, Kim NH, Kim MH, Park SH, Park WY, Kim YS, Lee BL, Cha CI, Chae YS, Lee KW
KMID: 2342972
J Korean Neurol Assoc.
2002 May;20(3):273-278.
BACKGROUND: Mutations in the human Cu, Zn-superoxide dismutase(SOD1) gene have been identified in some cases of familial amyotrophic lateral sclerosis(ALS). The aim of this study is to delineate the effect...