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Baseline use of hydroxychloroquine or immunosuppressive drugs and the risk of coronavirus disease 2019

Kim JW, Kwak SG, Lee H, Kim SK, Choe JY, Park SH

Background/Aims: The preventive role of hydroxychloroquine (HCQ) on coronavirus disease 2019 (COVID-19) remains unclear. The aim of this study was to examine the effects of HCQ and other immunosuppressive drugs...
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Health-related Quality of Life Outcomes of Adalimumab for Patients With Rheumatoid Arthritis in Korea

Lee Ms, Lee CH, Lee HS, Sung YK, Choi JR, Park K, Lim MK, Choi BY, Kim HA, Choi SW, Lee Y, Yoo WH

Objective: Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disorder that impairs patients’ overall health-related quality of life (HRQOL). In this study, we evaluated the effect of adalimumab in Korean...
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Janus kinase inhibitors for the treatment of rheumatoid arthritis

Jang SH, Ju JH

Rheumatoid arthritis is a chronic inflammatory destructive disorder that affects the joints, muscles, and tendons accompanying various extra-articular manifestations. Traditional disease-modifying anti-rheumatic drugs (DMARDs) represent the basic treatment for rheumatoid...
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Treatment strategy for patients with rheumatoid arthritis

Cho SK, Sung YK

Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the joints, causing joint destruction, functional disability, and reduced quality of life in patients. The aim of RA treatment is to...
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Combination of Methotrexate and Leflunomide for Adult-onset Still's Disease: A Case Report and Literature Review

Lee EE, Kim MJ, Song YW, Park JK

The treatment of adult-onset Still's disease (AOSD) aims to control systemic inflammation and prevent organ damage. Systemic inflammation can be controlled with corticosteroid (CS) monotherapy in most cases. However, symptoms...
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Simplified disease activity changes in real-world practice: a nationwide observational study of seropositive rheumatoid arthritis patients with moderate-to-high disease activity

Shin K, Kim SS, Lee SH, Hong SJ, Choi SJ, Choe JY, Lee SG, Cha HS, Lee EY, Park SH, Hur JW, Na SS, Suh CH, So MW, Choi SW, Sheen DH, Park W, Lee SS, Ryu WH, Kim JS, Song JS, Lee HS, Kim SH, Yoo DH

Background/Aims: The objective of this study was to compare changes in the simplified disease activity index (SDAI) between biologic (b) and conventional (c) disease-modifying antirheumatic drugs (DMARD) users with seropositive...
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Transaminase Changes in Korean Rheumatoid Arthritis Patients with Chronic Hepatitis C after Biologic Therapy

Kwon HM, Shin K, Moon JY, Lee SS, Chung WT, Lee J, Lee SH, Kang SW, Suh CH, Hong SJ, Song R, Choe JY, Song YW

OBJECTIVE: Coexisting chronic hepatitis C can be problematic when treating rheumatoid arthritis (RA). This study examined the changes in the transaminase and viral load in hepatitis C virus (HCV)-infected RA...
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Medication nonadherence in Korean patients with rheumatoid arthritis: the importance of belief about medication and illness perception

Suh YS, Cheon YH, Kim HO, Kim RB, Park KS, Kim SH, Lee SG, Park EK, Hur J, Lee SI

BACKGROUND/AIMS: To investigate medication nonadherence in Korean patients with rheumatoid arthritis (RA) and analyze related factors. METHODS: A total of 292 patients with RA participated in this study. Medication nonadherence, intentional...
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Risk of Herpes Zoster in Patients with Rheumatoid Arthritis Undergoing Biologic Disease-Modifying Therapy

Kwon HM, Lee SJ, Yang JA, Choi Y, Park JK, Lee EY, Song YW, Lee EB

OBJECTIVE: Rheumatoid arthritis (RA) patients suffer from an increased risk of herpes zoster (HZ) partially due to immunosuppressant medications. This study investigated HZ in RA patients treated with biologic disease-modifying...
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Comparative efficacy of biological agents in methotrexate-refractory rheumatoid arthritis patients: a Bayesian mixed treatment comparison

Choi M, Hyun MK, Choi S, Tchoe HJ, Lee SY, Son KM, Kim MJ, Jung YO, Kim HA

BACKGROUND/AIMS: Biological agents (biologics) targeting proinflammatory signaling have emerged as an important treatment option in rheumatoid arthritis (RA). Despite the clinical effectiveness of biologics for patients with RA who do...
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Pharmacologic treatment of rheumatoid arthritis

Cho SK, Bae SC

Rheumatoid arthritis (RA) is a systemic inflammatory disease that affects the joints. This chronic inflammatory condition causes joint destruction and functional disability, and reduces the quality of life of patients....
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Current concepts in the management of rheumatoid arthritis

Tanaka Y

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammation and joint destruction that causes significant morbidity and mortality. However, the combined use of methotrexate, a synthetic disease-modifying antirheumatic...
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Utilization Patterns of Disease-Modifying Antirheumatic Drugs in Elderly Rheumatoid Arthritis Patients

Jin XM, Lee J, Choi NK, Seong JM, Shin JY, Kim YJ, Kim MS, Yang BR, Park BJ

This study was conducted to investigate disease-modifying antirheumatic drug (DMARD) utilization in Korean elderly patients with rheumatoid arthritis (RA). We used data from January 1, 2005 to June 30, 2006...
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Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis

Jue DM, Jeon KI, Jeong JY

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by persistent joint swelling and progressive destruction of cartilage and bone. Current RA treatments are largely empirical in origin and their...
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