- Transduction of yeast cytosine deaminase mediated by HIV-1 Tat basic domain into tumor cells induces chemosensitivity to 5-fluorocytosine
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Lee H, Ryu J, Kim KA, Lee KS, Lee JY, Park JB, Park J, Choi SY
- KMID: 755664
- Exp Mol Med.
- 2004 Feb;36(1):43-51.
Enzyme/prodrug approach is one of the actively developing areas for cancer therapy. In an effort to develop more effective enzyme/prodrug systems, cell-permeable cytosine deaminase was produced by fusing yeast cytosine... -
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