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Updated treatment guideline of chronic spontaneous urticaria

Roh JY

Chronic spontaneous urticaria (CSU), also known as chronic idiopathic urticaria, is a common chronic inflammatory skin disorder that has a prevalence of 0.5% to 1% in the general population. It...
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Chronic Spontaneous Urticaria: Pathogenesis and Treatment Considerations

Kaplan AP

The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H1-receptor blockers are typically employed up to...
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A case of levocetirizine-induced fixed drug eruption and cross-reaction with piperazine derivatives

Kim MY, Jo EJ, Chang YS, Cho SH, Min KU, Kim SH

Fixed drug eruption is an uncommon adverse drug reaction caused by delayed cell-mediated hypersensitivity. Levocetirizine is an active (R)-enatiomer of cetirizine and there have been a few reports of fixed...
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An overview and considerations in prescribing H1-antihistamine

Choi YS, Park YM, Rha YH, Choi SH

H1-antihistamines have been prescribed widely for the treatment of allergic diseases, such as rhinitis, atopic dermatitis, and urticaria besides common colds since the 1940s. H1-antihistamines are classified by chemical structures...
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Treatment of Chronic Spontaneous Urticaria

Kaplan AP

Chronic spontaneous urticaria is defined as persistent symptoms of urticaria for 6 weeks or more. It is associated with autoimmunity in approximately 45 percent of patients. Therapy is often difficult...
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Investigation of the antiallergic activity of olopatadine on rhinitis induced by intranasal instillation of antigen in sensitized rats using thermography

Tamura T

BACKGROUND: The main symptoms of allergic rhinitis (AR) are sneezing, rhinorrhea and nasal obstruction. It was reported that the nasal skin temperature after intranasal administration of histamine or grass pollen...
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Comparative Analysis of Overdose with Common Sleep-aid Medications: Doxylamine vs Diphenhydramine

Ryu HS, Lee MJ, Park SS, Jeong WJ, Kim HJ

  • KMID: 2203733
  • J Korean Soc Clin Toxicol.
  • 2010 Dec;8(2):79-87.
PURPOSE: The previous studies on H1 antihistamine overdose have generally been limited to cases of acute doxylamine succinate (DS) poisoning, yet there have been some studies on diphenhydramine (DPH) overdosing....
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Analysis of the Effect of Oral Antihistamines in Patients with Chronic Urticaria in Terms of the Disease Outcome and Quality of Life

Lee EA, Kim HS, Lee JY, Kim HO, Park YM

  • KMID: 2088076
  • Korean J Dermatol.
  • 2010 Sep;48(9):758-765.
BACKGROUND: Chronic urticaria (CU) has a considerable influence on the well-being of patients and it has a negative impact on the quality of life (QOL). Oral antihistamines are commonly used...
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The Optimal Length of Time to Observe Patients with Contrast Media Anaphylaxis in the Emergency Department

Hwang SM, Lee SH, Yeom SR, Ryu JH, Jeong JW, Kim YI, Han SK

  • KMID: 2204097
  • J Korean Soc Clin Toxicol.
  • 2010 Jun;8(1):37-42.
PURPOSE: The purpose of this study was to determine the optimal length of time to observe patients with contrast media anaphylaxis in the Emergency Department. METHODS: This study included the patients...
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Antihistamine Pretreatment to Reduce Incidence of Withdrawal Movement After Rocuronium Injection

Lee HJ, Han SJ, Kim H, Lee IO, Kong MH, Kim NS, Lim SH, Lee MK

The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery...
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Block of hERG K+ Channel by Classic Histamine H1 Receptor Antagonist Chlorpheniramine

Hong HK, Jo SH

Chlorpheniramine is a potent first-generation histamine H1 receptor antagonist that can increase action potential duration and induce QT prolongation in several animal models. Since block of cardiac human ether-a-go-go-related gene...
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Diagnosis and treatment of allergic rhinitis

Lee JM

  • KMID: 1490318
  • Korean J Med.
  • 2009 Mar;76(3):268-273.
The diagnosis of allergic rhinitis can generally be made on the basis of the history and physical examination. The history helps establish seasonality, potentially inciting factors, and co-morbidities including sinusitis,...
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Efficacy and Safety of Fexofenadine in the Treatment of Pruritus Associated with Eczema

Kim YH, Ko JY, Moon KC, Park YM, Seo YJ, Yoo JH, Lee KH, Lee SC, Lee AY, Kim SE, Jang HS, Haw CL, Ro YS

  • KMID: 2302100
  • Korean J Dermatol.
  • 2008 Feb;46(2):151-159.
BACKGROUND: Fexofenadine (Allegra(R)) is a H1-receptor selective antihistamine which exhibits consistent efficacy and safety in the treatment of allergic diseases. We thought that fexofenadine may be useful in treatment of...
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Therapeutic Efficacy of Low-dose Cyclosporine in Chronic Idiopathic Urticaria

Kim BS, Cho HH, Ko HC, Kim SJ, Oh CK, Kwon KS, Kim MB

  • KMID: 2087382
  • Korean J Dermatol.
  • 2007 Jul;45(7):680-686.
BACKGROUND: Chronic idiopathic urticaria (CIU) has a major impact on patients' quality of life. However the management of CIU has sometimes been challenging to physicians, with little response to conventional...
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The Effect of H1-Receptor Antagonist on Hemodynamic Change during Anesthesia

Hahm TS, Kim CS, Koo MS, Shin BS, Hwang HY, Lee SM, Cho HS

baseline for safe use of a drug. RESULTS: SVR and PVR failed to show statistically significant changes. Heart rates were increased only at 2 minute after administration of chlorpheniramine maleate....
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Efficacy of a Combination with Pranlukast and Cetirizine in the Treatment of Allergic Rhinitis

Kim DJ, Jeon SY, Kim JP, Ahn SK, Kim BG

  • KMID: 2276214
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Sep;47(9):863-867.
BACKGROUND AND OBJECTIVES: It has been suggested that the combination of a leukotriene receptor antagonist with an antihistamine may have beneficial effects in the treatment of allergic rhinitis. The aim...
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Pharmacologic Therapy of Common Allergic Diseases

Park HS, Kim SH

No abstract available.
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Etiology and Treatment of Chronic Urticaria

Jee YK

Chronic urticaria is a well-known disease entity, characterized by the rapid appearance of frequently occurring, short-lived wheals, surrounded by a bright-red flare, and often accompanied by angioedema. Any pattern of...
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The Effect of Antihistamine of Endotoxin-induced Acute Lung Injury

Jung BH, Koh YS, Kim WD

  • KMID: 2425539
  • Tuberc Respir Dis.
  • 2002 Mar;52(3):219-229.
BACKGROUND: Sepsis-induced acute lung injury (ALI) is caused by many cellular and humoral mediators induced by an endotoxin. Histamine, which is widely distributed in the lungs and has been considered...
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A Case of Rhabdomyolysis after Doxylamine Overdose

Kim JC, Lee SA

  • KMID: 1852250
  • J Korean Neurol Assoc.
  • 2000 Jan;18(1):119-120.
We report a case of non-traumatic rhabdomyolysis after overdose of doxylamine succinate. A 22-year-old woman with reactive depression had an overdose of doxylamine with suicidal intent. She had decreased mental state,...
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