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Dedifferentiation of conditionally immortalized hepatocytes with long-term in vitro passage

Kim BH, Sung SR, Choi EH, Kim YI, Kim KJ, Dong SH, Kim HJ, Chang YW, Lee JI, Chang R

  • KMID: 927131
  • Exp Mol Med.
  • 2000 Mar;32(1):29-37.
The rat hepatocytes were immortalized using a temperature-sensitive mutant of SV40 large T antigen (tsT) to develop as a possible substitute for primary hepatocytes. Four rat hepatocyte lines that have...
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