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Changes of phospholipase D activity in TNF-alpha and anti-Fas/Apo1 monoclonal antibody induced apoptosis in HL-60 and A20 cells

Kang JH, Shin IC, Han JS

  • KMID: 754983
  • Exp Mol Med.
  • 1998 Mar;30(1):21-27.
The changes of phospholipase D (PLD) activity were investigated during the courses of apoptotic process induced by tumor necrosis factor (TNF)-alpha or anti-Fas/Apo1 antibody in human premyelocyte HL-60 and murine B cell...
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Cytolytic activity of mitogen activated old and young mouse spleen cells against tumor target cells expressing high or low levels of Fas antigen

Saxena RK, Adler WH

  • KMID: 755042
  • Exp Mol Med.
  • 1999 Sep;31(3):137-141.
Sensitivity of Fas expressing tumor cells (high levels in Hut78 & Jurkat; low levels in P815) toward the cytotoxic Con-A (5 microg/ml) activated spleen cells from young (12 to 16 week old...
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D60-sensitive tyrosine phosphorylation is involved in Fas-mediated phospholipase D activation

Kim JG, Shin IC, Lee KS, Han JS

  • KMID: 1457546
  • Exp Mol Med.
  • 2001 Dec;33(4):303-309.
Both Fas and PMA can activate phospholipase D via activation of protein kinase Cbeta in A20 cells. Phospholipase D activity was increased 4 fold in the presence of Fas and...
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Differential effects of Fas cross-linking on phospholipase D activation and related lipid metabolism in Fas-resistant A20 cells.

Lim SY, Lee SC, Shin IC, Han JS

  • KMID: 1380228
  • Exp Mol Med.
  • 2002 Jul;34(3):201-210.
A20 murine lymphoma cells undergoing Fas-mediated apoptosis showed increase in the activity of phospholipase D (PLD), which is involved in proliferative or mitogenic cellular responses. Using A20 cell lines that...
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Effects of Peroxisome Proliferator-activated Receptor-gamma Agonist on Fas-mediated Apoptosis in HT-29 Cells

Chung YW, Han DS, Kang EK, Lee JS, Lee HR, Kim JB, Park JY, Kim YS, Lee OY, Choi HS, Sohn JH, Yoo DH, Hahm JS

  • KMID: 772519
  • Korean J Gastroenterol.
  • 2003 Jul;42(1):35-41.
BACKGROUND/AIMS: Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) plays a critical role in adipocytes differentiation and insulin sensitivity and is also related to regulation of inflammation and cell proliferation. The aim of...
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