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Extrinsic Acquisition of CD80 by Antigen-Specific CD8⁺ T Cells Regulates Their Recall Immune Responses to Acute Viral Infection

Son J, Ha SJ

CD80 is mainly expressed on Ag-presenting cells (APCs) as a costimulatory molecule but is also detected on T cells. However, the origin and physiological role of CD80 on CD8⁺ T...
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Suppression of Tumor Formation and Induction of Natural Killer Cell Activity in BALB/c Nude Mice by Human B7-1 (CD80) Gene Transfer Subcutaneously Injected with Human Hepatocellular Carcinoma Cells (Huh-7)

Yoon SK, Kim TG, Cho HI, Lee BS, Cho SH, Han NI, Lee YS, Jang JW, Chung KW, Sun HS, Kim BS

  • KMID: 863146
  • Korean J Hepatol.
  • 2003 Jun;9(2):124-134.
BACKGROUND/AIMS: Immunogene therapy is extensively studied for a therapeutic modality of various cancers. This study was conducted to investigate the efficacy of immunogene therapy using the T-cell costimulatory molecule...
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Impaired responses of leukemic dendritic cells derived from a human myeloid cell line to LPS stimulation

Kim KD, Choi SC, Noh YW, Kim JW, Paik SG, Yang Y, Kim KI, Lim JS

  • KMID: 1105279
  • Exp Mol Med.
  • 2006 Feb;38(1):72-84.
Several myeloid leukemia-derived cells have been reported to possess the ability to differentiate into dendritic cells (DC). MUTZ-3, a myeloid leukemia cell line, responds to GM-CSF, IL-4 and TNF-alpha, and...
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