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The significance of CD44 variants expression in colorectal cancer and its regional lymph nodes

Chun SY, Bae OS, Kim JB

CD44 is a cell adhesion molecule with numerous isoforms created by mRNA alternative splicing. Expression of CD44 variants has been suggested to play a potential role in tumor progression and...
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The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study

Huang J, Zhang D, Xie F, Lin D

Increasing evidence suggests that cancer stem cells (CSCs) are responsible for tumor initiation and maintenance. Additionally, it is becoming apparent that cyclooxygenase (COX) signaling is associated with canine mammary tumor...
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Molecular genetic characterization of alternatively spliced CD44 transcripts in human stomach carcinoma

Kim YS, Chi SG, Kim YW, Park YK, Yoon C

CD44 is a member of cell surface glycoproteins which are involved in cell-matrix adhesion and tumor metastasis. Certain types of tumors express complex CD44 isoforms generated by alternative splicing...
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Acute UV Irradiation Increases Heparan Sulfate Proteoglycan Levels in Human Skin

Jung JY, Oh JH, Kim YK, Shin MH, Lee D, Chung JH

Glycosaminoglycans are important structural components in the skin and exist as various proteoglycan forms, except hyaluronic acid. Heparan sulfate (HS), one of the glycosaminoglycans, is composed of repeated disaccharide units,...
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