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The Studies for Interaction of MMP-2 Activating and Nonactivating Human Breast Cancer Cell Lines with Vitrogen

Lee MH, Thompson E

  • KMID: 2206467
  • J Korean Surg Soc.
  • 1999 Apr;56(4):479-485.
BACKGROUND: We have previously shown that the vimentin-positive subset of human breast cancer cell lines, which are more invasive in vitro and in vivo, can activate MMP-2 when cultured on...
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The Extracellular Matrix Affected Proliferation and Cell Adhesion of Human Adipose Tissue Derived Mesenchymal Stem Cells in vitro

Min SO, Lee SW, Choi SB, Kim KS

  • KMID: 1469756
  • Korean J Hepatobiliary Pancreat Surg.
  • 2009 Dec;13(4):198-204.
PURPOSE: Human mesenchymal stem cells (hMSCs) have the potency for self-renewal and differentiation into various kinds of cells. The hMSCs are obtained from the various tissues, including adipose tissue, bone...
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Overexpressions of Vimentin and Integrins in Human Metastatic Spine Tumors

Park SB, Ryu YJ, Chung YS, Kim CH, Chung CK

OBJECTIVE: To comparatively investigate the expression of several integrins in specimens of human bone metastases and degenerative bone tissue. METHODS: Degenerative cancellous tissue was obtained from a sample of human degenerative...
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The role of DNA methylation to type II collagen expression in dedifferentiation of articular chondrocytes

Kim YH, Hahn SB, Lee JW

  • KMID: 2104911
  • J Korean Orthop Res Soc.
  • 2003 Oct;6(2):214-222.
PURPOSE: We explored the possibility of DNA methylation as a mechanism of loss of type II collagen expression in dedifferentiating chondrocytes by culturing in monolayer. MATERIALS AND METHODS: Dedifferentiation was induced...
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beta1-integrin-dependent migration of microglia in response to neuron-released alpha-synuclein

Kim C, Cho ED, Kim HK, You S, Lee HJ, Hwang D, Lee SJ

Chronic neuroinflammation is an integral pathological feature of major neurodegenerative diseases. The recruitment of microglia to affected brain regions and the activation of these cells are the major events leading...
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The Expression of Integrins in Korean Breast Cancer Patients

Kim H, Jung YS, Kim HJ, Im HH, Lee JW, Byun JS, Kim MW, Park HB

  • KMID: 2209586
  • J Korean Surg Soc.
  • 2003 Jan;64(1):14-19.
PURPOSE: Integrins are cell surface proteins that anchor the cells to the extra-cellular matrix. It has recently been found that integrins are involved in proliferations, migration, differentiation and survival signal...
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CD98 Activation Increases the Invasion of Human Breast Carcinoma MCF-7 Cells

Kim SM, Kim JM, Jeon JS, Ahn ZS, Kim DY, Suh JS, Park KH, Park JH, Kim DJ, Hahn JH

  • KMID: 2283413
  • Korean J Phys Anthropol.
  • 2007 Sep;20(3):225-233.
CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates the func-tions of beta1 integrin, suggesting that it may play a role in tumor cell invasion. In this study, the...
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Effects of Mixed Leukocyte Reaction, Hydrocortisone, or Cyclosporine A on Expression of Adhesion Molecules by Endothelial and Mesangial cells

Leem CK, Hong SP, Park JK, Ahn JH, Lee TW, Cho BS, Yang MH, Kim MJ, Kim YH, Park WD

  • KMID: 2306382
  • Korean J Med.
  • 1997 Feb;52(2):156-164.
OBJECTIVES: ICAM-1, VCAM-1, and betal integrins mediate cell-cell or cell-matrix interactions. We investigated effects of mixed leukocyte reaction (MLR), cyclosporine A (CsA), or hydrocortisone (HC) on their expression by endothelial...
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Expression of Adhesion Molecules in Placenta and Correlation with Uterine Artery Doppler Velocimetry in Pregnancy-induced Hypertension

Park YW, Choi HM, Cho JS, Kim TY, Kim KS, Lim YK

  • KMID: 2260827
  • Korean J Obstet Gynecol.
  • 1997 Jun;40(6):1212-1221.
INTRODUCTION: The pathophysiology of PIH remains unclear. Recently, placental abnormalitiesare stressed as a possible cause of PIH. Abnormal shallow invasion of trophoblasts, confinedto decidua, without involving myometrium is...
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CD98 activation increases surface expression and clusteringof beta 1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms

Kim SM, Hahn JH

CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates beta 1 integrin- mediated cell adhesion. However, the molecular mechanisms underlying CD98-mediated activation of beta 1 integrin are presently unclear....
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In vivo characterization of the integrin beta3 as a receptor for Hantaan virus cellular entry

Song JW, Song KJ, Baek LJ, Frost B, Poncz M, Park KS

  • KMID: 755750
  • Exp Mol Med.
  • 2005 Apr;37(2):121-127.
Binding of viruses to cell surface molecules is an essential step in viral infection. In vitro studies suggested that the alpha v beta3 integrin receptor is the epithelial cell receptor...
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