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An Exploration of the Oryza sativa L. Cyanidin-3-glucoside on the Cognitive Function in Older Adults with Subjective Memory Impairment

Joo SH, Hahn C, Lim HK, Yoon KD, Yoon SH, Lee CU

OBJECTIVE: Cyanidin-3-glucoside (C3G), is a component of anthocyanin, have been considered to positively influence cognition and be beneficial for the prevention and treatment of dementia. We aimed to assess the...
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Evaluation of in vitro anti-oxidant and anti-inflammatory activities of Korean and Chinese Lonicera caerulea

Lee YS, Cho IJ, Kim JW, Lee SK, Ku SK, Lee HJ

BACKGROUND/OBJECTIVES: The honeysuckle berry (HB) contains ascorbic acid and phenolic components, especially anthocyanins, flavonoids, and low-molecular-weight phenolic acids. In order to examine the potential of HB as a hepatoprotective medicinal...
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Cyanidin-3-glucoside inhibits amyloid β₂₅₋₃₅-induced neuronal cell death in cultured rat hippocampal neurons

Yang JS, Jeon S, Yoon KD, Yoon SH

Increasing evidence implicates changes in [Ca²⁺]i and oxidative stress as causative factors in amyloid beta (Aβ)-induced neuronal cell death. Cyanidin-3-glucoside (C3G), a component of anthocyanin, has been reported to protect...
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Endothelium Independent Effect of Pelargonidin on Vasoconstriction in Rat Aorta

Min YS, Yoon HJ, Je HD, Lee JH, Yoo SS, Shim HS, Lee HY, La HO, Sohn UD

In this study, we investigated the effects of pelargonidin, an anthocyanidin found in many fruits and vegetables, on endothelium-independent vascular contractility to determine the underlying mechanism of relaxation. Isometric contractions...
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Black Rice (Oryza sativa L., Poaceae) Extract Reduces Hippocampal Neuronal Cell Death Induced by Transient Global Cerebral Ischemia in Mice

Hwang SN, Kim JC, Bhuiyan MI, Kim JY, Yang JS, Yoon SH, Yoon KD, Kim SY

Rice is the most commonly consumed grain in the world. Black rice has been suggested to contain various bioactive compounds including anthocyanin antioxidants. There is currently little information about the...
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Survey on utilization and demand for national food composition database

Lee HS, Chang MJ, Kim HY, Shim JS, Lee JS, Kim KN

PURPOSE: This study was performed to evaluate the utilization of a current national Food Composition Database (FCDB) and to investigate demand for nutrients that should be added or supplemented in...
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Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages

Kim JN, Han SN, Ha TJ, Kim HK

BACKGROUND/OBJECTIVES: Oxidative stress is closely related with inflammation and development of many diseases. Black soybean seed coat contains high amount of anthocyanins, which are well-known for free radical scavenging activities....
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Cancer-preventive Properties of an Anthocyanin-enriched Sweet Potato in the APCMIN Mouse Model

Asadi K, Ferguson L, Philpott M, Karunasinghe N

BACKGROUND: Anthocyanin-rich foods and preparations have been reported to reduce the risk of life-style related diseases, including cancer. The SL222 sweet potato, a purple-fleshed cultivar developed in New Zealand, accumulates...
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Estimated flavonoid intakes according to socioeconomic status of Korean adults based on the Korea National Health and Nutrition Examination Survey 2007~2012

Kim SA, Hei Y, Jun S, Wie GA, Shin S, Hong E, Joung H

PURPOSE: The purpose of this study was to estimate the dietary flavonoid intakes of Korean adults according to socioeconomic status. METHODS: Using data from the 2007~2012 Korea National Health and Nutrition...
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Antimutagenic and Antioxidant Activities of Thai Rice Brans

Insuan O, Chariyakornkul A, Rungrote Y, Wongpoomchai R

BACKGROUND: Rice bran is the outer layer of the rice grain, and contains high amounts of bioactive phytochemicals. Here, we investigated and compared chemopreventive properties of purple and white rice...
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Anthocyanins from Clitoria ternatea Attenuate Food-Borne Penicillium expansum and its Potential Application as Food Biopreservative

Leong CR, Kamarul Azizi MA, Taher MA, Wahidin S, Lee KC, Tan WN, Tong WY

Clitoria ternatea or Commonly known blue pea, is a perennial climber crop native to Asian countries. The current study was aimed to evaluate the antimicrobial activity C. ternatea extract on...
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Blueberry, blackberry, and blackcurrant differentially affect plasma lipids and pro-inflammatory markers in diet-induced obesity mice

Kim B, Lee SG, Park YK, Ku CS, Pham TX, Wegner CJ, Yang Y, Koo SI, Chun OK, Lee JY

BACKGROUND/OBJECTIVES: Evidence indicates that berry anthocyanins are anti-atherogenic, antioxidant, and anti-inflammatory. However, berries differ vastly in their anthocyanin composition and thus potentially in their biological and metabolic effects. The present...
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Cytoprotective Mechanism of Cyanidin and Delphinidin against Oxidative Stress-Induced Tenofibroblast Death

Nam DC, Hah YS, Nam JB, Kim RJ, Park HB

Age-related rotator cuff tendon degeneration is related to tenofibroblast apoptosis. Anthocyanins reduce oxidative stress-induced apoptotic cell death in tenofibroblasts. The current study investigated the presence of cell protective effects in...
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Suppression of β-catenin Signaling Pathway in Human Prostate Cancer PC3 Cells by Delphinidin

Lee W, Yun JM

Delphinidin possesses strong anti-oxidant, anti-inflammatory, and anti-cancer properties. Suppression of the Wnt/β-catenin signaling pathway is a potential strategy for chemoprevention and therapy. As aberrant activation of the β-catenin signaling pathway...
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Estimated dietary flavonoids intake of Korean adolescent: Based on the Korea National Health and Nutrition Examination Survey 2007~2012

Kim SA, Jun S, Joung H

PURPOSE: The purpose of this study was to estimate dietary flavonoids intake of Korean adolescents. METHODS: Using data from the 2007-2012 Korean National Health and Nutrition Examination Survey, a total of...
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Chemopreventive Action of Anthocyanin-rich Black Soybean Fraction in APC(Min/+) Intestinal Polyposis Model

Park MY, Kim JM, Kim JS, Choung MG, Sung MK

BACKGROUND: Anthocyanins have been shown to inhibit cancer cell growth by suppressing oxidative stress and inflammatory responses. The purpose of this study was to investigate the effects of an anthocyanin-rich...
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Effects of the C3G/D3G anthocyanins-rich black soybean testa extracts on improvement of lipid profiles in STZ-induced diabetic rats

Park SY, Pak S, Kang SJ, Kim NY, Kim DS, Kim MJ, Kim SA, Kim JY, Park SY, Park SH, Youn CR, Lee BR, Lee HE, Choi SY, Choi HW, Heo JY, Hwang AY, Lee MS

PURPOSE: The purpose of this study was to examine the effect of black soybean (CJ-3) testa extracts on lipid profiles in streptozotocin (STZ)-induced diabetic rats. METHODS: One control group and four...
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Rapid Isolation of Cyanidin 3-Glucoside and Peonidin 3-Glucoside from Black Rice (Oryza sativa) Using High-Performance Countercurrent Chromatography and Reversed-Phase Column Chromatography

Jeon H, Choi J, Choi SJ, Lee CU, Yoon SH, Kim J, Yoon KD

Anthocyanins are water soluble plant pigments which are responsible for the blue, red, pink, violet colors in several plant organs such as flowers, fruits, leaves and roots. In recent years,...
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Anthocyanins From the Fruit of Vitis coignetiae Pulliat Potentiate the Cisplatin Activity by Inhibiting PI3K/Akt Signaling Pathways in Human Gastric Cancer Cells

Lu JN, Lee WS, Nagappan A, Chang SH, Choi YH, Kim HJ, Kim GS, Ryu CH, Shin SC, Jung JM, Hong SC

BACKGROUND: Cisplatin (cis-diaminedichloroplatinum, CDDP) is a widely used chemotherapeutic agent for the treatment of many cancers. However, initial resistance to CDDP is a serious problem in treating these cancers. Vitis...
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Effects of an aqueous extract of purple sweet potato on nonalcoholic fatty liver in high fat/cholesterol-fed mice

Lee YJ, Yang YK, Kim YJ, Kwon O

PURPOSE: Anthocyanins from purple sweet potato (PSP) have been investigated in vitro and in animals and found to have a protective effect against oxidative hepatic damage. In this study, we...
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