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COX-2 inhibits anoikis by activation of the PI-3K/Akt pathway in human bladder cancer cells

Choi EM, Kwak SJ, Kim YM, Ha KS, Kim JI, Lee SW, Han JA

  • KMID: 1056232
  • Exp Mol Med.
  • 2005 Jun;37(3):199-203.
Cyclooxygenase-2 (COX-2) has been reported to be associated with tumor development and progression as well as to protect cells from apoptosis induced by various cellular stresses. Through a tetracycline-regulated COX-2...
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PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase

Lee Y, Kim SJ, Min HJ, Jo JY, Park EH, Koh SS

Pancreatic cancer is a notorious disease with a poor prognosis and low survival rates, which is due to limited advances in understanding of the molecular mechanism and inadequate development of...
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The Role of Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN) in Lung Cancer

Lee HK, Lee YC

  • KMID: 2325380
  • J Lung Cancer.
  • 2004 Mar;3(1):1-5.
Lung cancer remains the primary cause of cancer-related death in the world, and the number of cases continues to increase. Like any other human cancer, the development of lung cancer...
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rBMSCs/ITGA5B1 Promotes Human Vascular Smooth Muscle Cell Differentiation via Enhancing Nitric Oxide Production

Zhang Y, Ding J, Xu C, Yang H, Xia P, Ma S, Chen H

BACKGROUND AND OBJECTIVES: Previous studies have shown that integrins alpha5beta1 (ITGA5B1) gene-modified rat bone marrow mesenchymal stem cells (rBMSCs) could prevent cell anoikis and increase the nitric oxide (NO) production....
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