- Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins
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Ha SH, Kim HK, Anh NT, Kim N, Ko KS, Rhee BD, Han J
- KMID: 2388698
- Korean J Physiol Pharmacol.
- 2017 Sep;21(5):531-546.
- doi: 10.4196/kjpp.2017.21.5.531
Activation of Toll-like receptor-4 (TLR-4) in articular chondrocytes increases the catabolic compartment and leads to matrix degradation during the development of osteoarthritis. In this study, we determined the proteomic and... -
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- Lipocortin 1 mediates the suppressive effects of dexamethasone on CoNinduced proliferative response and nitric oxide production in rat splenic leukocytes
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Jang YJ, Park H, Kang SA, Yan SJ, Na DS
- KMID: 2285163
- Korean J Physiol Pharmacol.
- 1997 Feb;1(1):91-96.
Lipocortin 1 has been proposed as a putative mediator of anti-inflammatory actions of glucocorticoids. We investigated the role of lipocortin 1 in the effect of dexamethasone using rat splenic leukocytes. Concanavalin A(ConA; 1-microgram/ml)... -
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- The effects of differentiation and glucocorticoid treatment on the expression of lipocortin 1 in U937 cells
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Cho YJ, Moon HB, Na DS
- KMID: 1543163
- Korean J Allergy.
- 1997 Jun;17(2):119-128.
Lipocortin represents a family of similar Ca++ depentent phospholipid-binding proteins capable of blocking the activity of phospholipase A2 (PLA2) in vitro. Generally, these proteins are believed to inhibit the release... -
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