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Dairy consumption and risk of type-2 diabetes: the untold story

Gudi SK

The role of dairy products in human health has been extensively studied for decades; however, evidence regarding dairy consumption and risk of type 2 diabetes (T2D) remains controversial and uncertain....
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Two cases of 17α-hydroxylase/17,20-lyase deficiency caused by the CYP17A1 mutation

Lee HI, Kwon A, Suh JH, Choi HS, Song KC, Chae HW, Kim HS

17α-hydroxylase/17,20-lyase deficiency, caused by mutations in the cytochrome P450 family 17 subfamily A member 1 gene (CYP17A1), is an extremely rare form of congenital adrenal hyperplasia that is characterized by...
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Thyroid imaging study in children with suspected thyroid dysgenesis

Chun S, Lee YS, Yu J

Purpose: Thyroid dysgenesis is one of the most common causes of permanent congenital hypothyroidism. Thyroid ultrasonography or scan is used to detect thyroid dysgenesis. We analyzed the sensitivity and specificity...
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Congenital hyperinsulinism: 2 case reports with different rare variants in ABCC8

Mouron-Hryciuk J, Stoppa-Vaucher S, Busiah K, Bouthors T, Antoniou MC, Jacot E, Brusgaard K, Christesen HT, Hussain K, Dwyer A, Roth-Kleiner M, Hauschild M

Congenital hyperinsulinism (CHI) is a rare glucose metabolism disorder characterized by unregulated secretion of insulin that leads to hyperinsulinemic hypoglycemia (HH). Most cases are caused by mutations in the KATP-channel...
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Changes in anthropometric indices among Korean school students based on the 2010 and 2018 Korea School Health Examination Surveys

Seo MY, Kim SH, Park MJ

Purpose: This study sought to identify changes in anthropometric values among Korean school students by comparing the most recent nationwide data with previous data. Methods: Data from the Korea School Health...
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Role of obesity-induced inflammation in the development of insulin resistance and type 2 diabetes: history of the research and remaining questions

Kim J, Lee J

The prevalence of obesity has increased alarmingly both worldwide and in Korea. This has also dramatically increased the prevalence of chronic obesity-associated diseases, including type 2 diabetes (T2D). Extensive studies...
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Complete androgen insensitivity syndrome and risk of gonadal malignancy: systematic review

Barros BA, Oliveira LRd, Surur CRC, Barros-Filho AdA, Maciel-Guerra AT, Guerra-Junior G

Complete androgen insensitivity syndrome (CAIS) is a rare condition characterized by 46,XY karyotype, female external genitalia, absence of uterus, and testes located intra-abdominally, in the inguinal ring or in the...
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Novel function of adrenocorticotropic hormone in the stimulation of vascular endothelial growth factor release in healthy children and adolescents: a proof-of-concept study

Heksch R, Bowden S, Hoffman R

Purpose: To assess the effect of adrenocorticotropic hormone (ACTH) on plasma vascular endothelial growth factor (VEGF) levels in healthy children and adolescents and to inform future work on the effects...
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A cell function study on calcium regulation of a novel calcium-sensing receptor mutation (p.Tyr825Phe)

Moon JE, Yang HY, Wee G, ParK SH, Ko CW

Purpose: Autosomal dominant hypocalcemia with hypercalciuria is a genetic disease characterized by hypoparathyroidism with hypercalciuria. We discovered a novel variant (p.Tyr825Phe[Y825F]) of the CASR gene in a neonate with congenital...
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Factors influencing growth hormone therapy effect during the prepubertal period in small for gestational age children without catch-up growth

Kum CD, Rho JG, Park HK, Lee HS, Hwang JS

Purpose: Because small for gestational age (SGA) children who fail to experience catch-up growth have an increased risk of short stature in adulthood, growth hormone (GH) treatment is recommended for...
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