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A Boy with Adrenocortical Tumor Who Progressed to Central Precocious Puberty after Surgery

Chueh HW, Bak NR, Kim MJ, Yoo JH, Rho MS, Cho WY

Adrenocortical tumors in children are rare and show various clinical symptoms. We present an 8-year-old boy with peripheral precocious puberty caused by adrenocortical tumor. He showed elevated serum DHEA-S and...
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A Case of Neonatal Dual Ectopic Thyroid Glands with Congenital Hypothyroidism

Cho HJ, Lee HY, Park SA

An ectopic thyroid occurs when thyroid tissue has not properly migrated from the foramen cecum to the fourth tracheal ring along the midline of the ventral portion of the neck,...
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The Clinical Course and Prognostic Factors to Medical Treatment of Graves' Disease in Children and Adolescents

Kim WK, Ahn BH, Han HS

PURPOSE: The aim of this study was to observe clinical course including remission rate during antithyroid medication for Graves' disease in children and adolescents, and to evaluate factors related to...
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A Case of adrenocortical oncocytoma Presenting with Peripheral Precocious Puberty

Oh SH, Jung CW, Lee J, Lee BH, Kim DY, No DY, Yoo SH, Choi JH, Yoo HW

Adrenocortical oncocytoma is a rare adrenal gland tumor, and in most cases, benign and non-functioning. Functional adrenocortical oncocytoma has only been reported in eleven cases worldwide, including three children. These...
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Congenital Adrenal Agenesis Presented with Adrenal Insufficiency

Park HK, Shim EJ, Lee KS, Hwang IT

We report a very rare case of congenital adrenal agenesis presented with adrenal insufficiency in a 4-day-old female newborn. She was admitted with darkish skin color and seizure. Her external...
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Insulin-Like Growth Factor 1 Actions in Developing Brain and the Interaction with Wnt Pathway

Lee SY

Insulin like growth factor (IGF)-1 signaling through type 1 IGF receptor (IGF1R) is essential to the normal growth and development of the central nervous system. IGF-1 stimulates proliferation of neural...
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Serum Alkaline Phosphatase Levels in 10-20 Year Old Healthy Korean Children and Adolescents: Based on the 2009 Korean National Health and Nutrition Examination Survey

Seo JY, Chae JD, Park HK, Kim DH, Lee JA, Lim JS

PURPOSE: Serum alkaline phosphatase (sALP) levels show great variation with age and sex in children and adolescents. We aimed to study pediatric age- and sex-specific reference ranges for sALP and...
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Evaluation of Information of Websites on Precocious Puberty

Kim BK, Park SH, Sung HU, Park SY, Kwon YS, Jun YH, Kim SK, Lee JE

PURPOSE: To evaluate the quality and scientific accuracy of internet information regarding precocious puberty. METHODS: We identified websites by entering "precocious puberty" or "early puberty" into 5 search engines from May...
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Emotional and Behavioral Problems in Children with Chronic Physical Illness

Shin YM, Cho SM

Children with chronic illness are known to have an increased risk of emotional and behavioral problems. Many studies have been conducted to identify risk and resistance factors associated with differences...
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Frequencies and Related Factors for Microvascular Complications in Patients with Type 1 Diabetes

Kwon AR, Lee S, Chae HW, Kim DH, Kim HS

PURPOSE: We observed the frequencies of microvascular complications and their related factors in patients with type 1 diabetes. METHODS: Two hundred seventy one patients (111 males and 160 females, mean age...
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