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A Worrisome Case of Early In Situ Melanoma on the Leg: A Multicomponent Pattern in Dermoscopy Supportive of Malignancy

Kiyohara T, Tanimura H

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A Calculating Method for Nail Growth Using CO 2 Laser Drilling and Dermoscopy

Sohng C, Kim JY

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A Case of Papillary Thyroid Cancer Metastasis to Skin: A Solitary Nodule Next to a Scar

Tiao J, McGee J, Chung HJ

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Linear Lichen Sclerosus Mimicking the Halo Nevus

Lee HY, Oh DY, Koo DW, Lee JS

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A Case of New-Onset Vitiligo in a Healthy Volunteer After Administration of Adalimumab

Yang HJ, Lee WJ, Lee MW, Choi JH, Chang SE

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Focal CK7 Positivity in Pagetoid Bowen’s Disease: A Mimic of Extramammary Paget’s Disease

Lee JH, Lee SK, Kim JH, Kim HY, Suh JH, Kim MS, Lee UH

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Eccrine Nevus on the Neck: A Case Report and Review of the Literature

Lee H, Cho S

Eccrine nevus is an extremely rare benign cutaneous hamartoma that usually occurs in childhood and adolescence. It has a wide range of clinical manifestations, and histological findings reveal a proliferation...
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Association of Atopic Dermatitis with Dyslipidemia in Adolescents: A Cross-Sectional Study

Leigh JH, Park HJ, Chun SM, Min YS, Choi M

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A Case of Newly Developed Pemphigus Foliaceus and Possible Association with Alternative Bee-Venom Therapy

Yoo SA, Park HE, Kim M

Bee-venom is composed of a variety of peptides, enzymes, and biogenic amines, and is demonstrated to have both anti-inflammatory and immune-stimulatory effects in human body. Pemphigus foliaceus (PF) is a...
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Novel Point Mutation of EBSS Gene Coexisted with 1p36 Deletion

Zheng Y, Xu Q, Lai W

EBSS (epidermolysis bullosa simplex superficialis) is mainly caused by gene mutations which targeted protein as plakophilin-1, desmoplakin and keratins. 1p36 gene deleted could cause typical clinical manifestations and might also...
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Prognostic Significance of Epidermal Growth Factor Receptor Expression in Distant Metastatic Melanoma from Primary Cutaneous Melanoma

Lee KH, Suh HY, Lee MW, Lee WJ, Chang SE

Background: Epidermal growth factor receptor (EGFR) is overexpressed in many cancers. However, EGFR expression in melanoma and its role are conflicting. Objective: This study aimed to evaluate EGFR expression in...
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Infantile Hemangiomas with Minimal and Arrested Growth: Clinical Features and Treatment Outcomes with 0.5% Topical Timolol Maleate

Bae KN, Shin K, Kim HS, Kim BS, Kim MB, Ko HC

Background: A minority of infantile hemangiomas showing minimal or arrested growth (IH-MAGs) have been recognized in the literature. Nevertheless, the clinical features and treatment outcomes of IH-MAGs have not been...
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Effectiveness of Cytochrome c Oxidase Subunit 1 Gene Nested Polymerase Chain Reaction Compared to Dermoscopy or Microscopy Alone for the Detection and Diagnosis of Sarcoptes scabiei var. hominis Infection

Yang SY, Kim SS, Kim CW

Background: While microscopy (MS) evaluation of skin scrapings has a 100% positive predictive value and specificity by definition for scabies diagnosis, it has low sensitivity. Dermoscopy (DS) has not yet...
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Periocular Dark Circles: Correlates of Severity

Lim HGY, Fischer AH, Sung S, Kang S, Chien AL

Background: Periocular dark circles (PDCs) are a common cosmetic complaint. Grading systems based on objective measures have been used but no standard system is in place. Objective: To determine factors associated...
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Sweet’s Syndrome Limited on the Palms and Soles: A Case Report

Lim JH, Sim WY, Lew BL

Sweet’s syndrome was first described as a reactive dermatosis characterized by sudden onset of fever, leukocytosis, and erythematous plaques infiltrated with neutrophils. Therefore, Sweet’s syndrome is also known as acute febrile...
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Azidothymidine Downregulates Insulin-Like Growth Factor-1 Induced Lipogenesis by Suppressing Mitochondrial Biogenesis and Mitophagy in Immortalized Human Sebocytes

Yoo JG, Li XM, Lee JK, Park S, Hong D, Jung KE, Lee Y, Seo YJ, Kim CD, Shin JM, Choi CW

Background: Increased sebum secretion is considered the main causative factor in the pathogenesis of acne. There is an unmet pharmacological need for a novel drug that can control sebum production...
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Red Ginseng Acidic Polysaccharides Promote the Expression of Acne-Related Inflammatory Biomarkers in Lipopolysaccharide-Treated Sebocytes and Outer Root Sheath Cells and Cutibacterium acnes-Injected Mice

Lee HJ, Kwack MH, Lee WJ

Background: Although ginseng has beneficial effects largely related to their constituent ginsenosides, pharmacological effects of non-ginsenosides have been reported. Acidic polysaccharides of red ginseng (RGAP) are among the non-ginsenoside constituents...
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NaHCO 3- and NaCl-Type Hot Springs Enhance the Secretion of Inflammatory Cytokine Induced by Polyinosinic-Polycytidylic Acid in HaCaT Cells

Park SH, Jung BY, Lee SY, Yu DS, Woo SY, Yun ST, Lee JT, Kim JW, Lee YB

Background: Hot springs have been traditionally used as an alternative treatment for a wide range of diseases, including rheumatoid arthritis, bronchial asthma, diabetes, hypertension, psoriasis and atopic dermatitis. However, the...
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Toll‐Like Receptor 7 (TLR7) Mediated Transcriptomic Changes on Human Mast Cells

Cho KA, Choi DW, Park M, Kim YH, Woo SY

Background: Mast cells are skin immune sentinels located in the upper dermis, where wheal formation and sensory nerve stimulation take place. Skin inflammation is occasionally accompanied by mast cell-driven responses...
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