- Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level
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Pearce LV, Ann J, Blumberg P, Lee J
- KMID: 2456217
- Biomol Ther.
- 2019 Sep;27(5):435-441.
- doi: 10.4062/biomolther.2019.013
The capsaicin receptor TRPV1 (transient receptor potential vanilloid 1) has been an object of intense interest for pharmacological development on account of its critical role in nociception. In the course... -
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- Decrease in spectral entropy by low tidal volume ventilation-associated severe hypercapnia: a case report
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Ann J, Jung SM, Park SJ
- KMID: 2377424
- Korean J Anesthesiol.
- 2017 Apr;70(2):213-216.
- doi: 10.4097/kjae.2017.70.2.213
Severe hypercapnia can be predicted by a decrease in cerebral electrical activity. The authors describe a sudden decrease in spectral entropy due to severe hypercapnia-induced respiratory acidosis in a patient... -
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- An Aminopropyl Carbazole Derivative Induces Neurogenesis by Increasing Final Cell Division in Neural Stem Cells
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Shin JY, Kong SY, Yoon HJ, Ann J, Lee J, Kim HJ
- KMID: 2382359
- Biomol Ther.
- 2015 Jul;23(4):313-319.
- doi: 10.4062/biomolther.2015.016
P7C3 and its derivatives, 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(p-tolylamino)propan-2-ol (1) and N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-hydroxypropyl)-N-(3-methoxyphenyl)-4-methylbenzenesulfonamide (2), were previously reported to increase neurogenesis in rat neural stem cells (NSCs). Although P7C3 is known to increase neurogenesis by protecting... -
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