- The translation inhibitor anisomycin induces Elk-1-mediated transcriptional activation of egr-1 through multiple mitogen-activated protein kinase pathways
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Shin SY, Lee JH, Min B, Lee YH
- KMID: 1115946
- Exp Mol Med.
- 2006 Dec;38(6):677-685.
The early growth response-1 gene (egr-1) encodes a zinc-finger transcription factor Egr-1 and is rapidly inducible by a variety of extracellular stimuli. Anisomycin (ANX), a protein synthesis inhibitor, stimulates mitogen-activated... -
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- The Effects of Epidermal Growth Factor on c-Fos mRNA Proto-Oncogene Expression in The Human Endometrial Cancer Cell Line , HEC-1-A
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Park JY, Park YK, Kang JS
- KMID: 2260921
- Korean J Obstet Gynecol.
- 1998 Apr;41(4):1114-1125.
Growth factors stimulate cell proliferation and differentiation through binding to specific high affinity receptors. Signalling pathway that mediate the normal functions of growth factors are commonly subverted in cancers. Proto-oncogenes... -
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- Recombinant Human Thioredoxin-1 Protects Macrophages from Oxidized Low-Density Lipoprotein-Induced Foam Cell Formation and Cell Apoptosis
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Zhang H, Liu Q, Lin JL, Wang Y, Zhang RX, Hou JB, Yu B
- KMID: 2429051
- Biomol Ther.
- 2018 Mar;26(2):121-129.
- doi: 10.4062/biomolther.2016.275
Oxidized low-density lipoprotein (ox-LDL)-induced macrophage foam cell formation and apoptosis play critical roles in the pathogenesis of atherosclerosis. Thioredoxin-1 (Trx) is an antioxidant that potently protects various cells from oxidative... -
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- c-Jun N-terminal kinase is involved in motility of endothelial cell
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Shin EY, Kim SY, Kim EG
- KMID: 1457542
- Exp Mol Med.
- 2001 Dec;33(4):276-283.
Cell motility is essential for a wide range of cellular activities including anigogenesis as well as metastasis of tumor cells. Ras has been implicated in cell migration and invasion, and... -
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